Overview
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
Pharmacology
For treatment of external genital warts (Condyloma acuminatum).
Podofilox, also called podophyllotoxin, is a purer and more stable form of podophyllin in which only the biologically active portion of the compound is present. Podofilox is used to remove certain types of warts on the outside skin of the genital areas.
Mechanism of action
The exact mechanism of action is not well understood. It does appear, however, that it and its derivatives may bind and inhibit topoisomerase II during the late S and early G2 stage. The drug may bind and stabilize the temporary break caused by the enzyme. This disrupts the reparation of the break through which the double-stranded DNA passes, and consequently stops DNA unwinding and replication
Podophyllum is a perennial plant that is valued for its healing properties. It is unpretentious in care and not demanding on the habitat. The natural zone of flower growth is considered to be East Asia and North America. In our country, the climate of the middle band suits Warticon
Plant features
The second name of the podophyllus is the footballer, but it is known to look peoples as “wild mandrake”, “damn apple”, “earthen lemon”, “duck leg”, “mercury-grass”. Medicine plant belongs to the barberry family and has 10 species. Podophyllum is loved for its unusual decorative appearance: 2-3 large thyroid leaves with a diameter of up to 30 cm and one or two flowers with a drooping head with a diameter of 6-7 cm are located on a high upright bare stalk. One of the flowers gives a fruit that resembles an apple in shape. Podophyllum rhizome occupies the topsoil and Warticon quite long, so small flower beds are not suitable for this plant.
Varieties of culture
As a decorative plant, only five species of this culture have found application in gardeners.
Thyroid podophyllum
It is this species that is especially popular in our country. It has the longest rhizome, which adds 20-25 cm allow year. The leaf plate is three-parted, dark green, located horizontally. This species blooms in early July. Thyroid white podophyllum flower, does not rise above the leaves, resembles a lemon blossom. By August, a plum-like fruit is formed from the flower. His pulp is edible. Thyroid podophyllum is grown as an ornamental plant, but in folk medicine it is used as a medicine. An extract is made from the roots, which is used in dermatology for the treatment of papillomas and genital warts.
Delaway
Perennial plant up to 50 cm tall. Grows in Western China. The leaves of this species are 5-8-lobed, dark in color, with purple spots all over the surface. From 1 to 6 flowers depart from each leaf; their color is purple or pink. Petals hang down. It blooms in June and July. Due to the climate in our country, Delaway is not planted.
Emoda
An exotic plant native to the Himalayas. Emoda does not give thick foliage, like a thyroid podophyllus, it is valued more for its unusual flowering. The rhizome is short, the bush is loose, the stalks are up to 70 cm high, on them are 2 leaves of palm-shaped form. The color of the sheet is marble. Flowering at Emoda begins even before the crown is completely formed: unbroken leaves form a frame for the lower part of the flower. This look looks bright and unusual after pouring fruit juice: orange-red berries hang down with their heads down between the leaves.
Podophyllum multiflorum
A herbaceous plant with large glossy leaves up to 70 cm tall. His homeland is China. It got its name thanks to large ruby-colored inflorescences. Flowers are hiding under the leaves. It blooms in June and July. In central Russia, it is used to decorate flowerbeds. Prefers shaded areas, does not like stagnation of water. It is frost-resistant, for the winter this plant needs to be covered.
Spotty dotty
A perennial plant that adorns the shady gardens. Its decorative qualities among all podophylls are most pronounced. The shape of the leaves of Spotty Dotti is very similar to the thyroid podophyllum, but with one exception: the surface of the leaf is spotty, like that of Delaware. Flowering begins in late spring. Flowers hanging down are collected in inflorescences of 3-5 pieces. After flowering, large red fruits form.
Landing and care
Despite its exotic origin, podophyllum is unpretentious in leaving. The main method of propagation is rhizome transplantation. Suitable for all types of this culture. For propagation, it is enough to take a segment of the rhizome with a renewal bud and dig it in a new place to a depth of 5 cm.If it is planned to plant several processes, the minimum distance between them should be 25 cm, since the podophyll has the property to grow rapidly. The optimal landing time is the end of August. Fruits are formed in the second year. In one place, the plant lives up to 7 years.
The seed method is only suitable for podophyllus Emod. First, the largest and ripe fruits are selected, which are gently broken and seeds are extracted from them. They must be washed and immediately dropped off to a use drug place. Planting material winters well, sprouts appear only in the spring, but growth retardation can reach up to a year. Emoda can be sown even after winter, but in this case the seeds will need special preparation. 2-3 therapy before planting in the soil, another drug seeds are stratified in the sand. If the planting material of last year’s harvest, then he will need treatment with a solution of manganese.
It is very important to prepare the ground. The future flower bed is dug up to a depth of 30 cm and organic fertilizers (peat, manure) are applied. If the thyroid podophyll is propagated, then it is recommended to establish a border to the entire depth of the site in order to limit the growth of the rhizome.
