Articaine and epinephrine is a combination medicine used to numb your mouth for a dental procedure.
Ubistesin is a drug made in Cyprus, New Zealand. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Articaine is a complete analogue of Ubistesin. It has the same composition, dosage and methods of use. Also Articaine has a lower cost compared to Ubistesin.
To buy Ubistesin, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Get emergency medical help if you have even mild symptoms: Kidney Problems Causing A Decreased Amount Of Urine To Be Passed Decreased Pupil Size Dry Mouth Head Pain Problems With Eyesight Dizzy Shaking Extremities Apprehension
Warnings
To make sure articaine and epinephrine is safe for you, tell your doctor if you have:
- a heart rhythm disorder;
- low or high blood pressure;
- asthma or a sulfite allergy; or
- a history of seizures.
It is not known whether articaine and epinephrine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
You should not receive articaine and epinephrine if you are allergic to any type of numbing medicine.
Interactions
Methemoglobinemia Associated Agents: May enhance the adverse/toxic effect of Local Anesthetics. Specifically, the risk for methemoglobinemia may be increased. Monitor therapy
Monoamine Oxidase Inhibitors: May enhance the hypertensive effect of EPINEPHrine (Systemic). Monitor therapy
Benperidol: May diminish the therapeutic effect of EPINEPHrine (Systemic). Monitor therapy
Food interaction
Pregnancy
- There is no evidence of risk in pregnancy.
- The drug should not be given to pregnant women, because of risk of virilization of a female fetus, particularly when high doses are given for several weeks.
Overview
Bans to use
When is it forbidden to use articaine? The instruction for use states that preparations based on this component are contraindicated in:
- chronic hypoxia;
- high sensitivity to articaine, as well as to other local anesthetics belonging to the amide group;
- any diseases of the central nervous system;
- megaloblastic B12-deficient anemia;
- bronchial asthma;
- angle-closure glaucoma;
- paroxysmal tachycardia;
- acute heart failure;
- atrial tachyarrhythmia;
- severe violations of cardiac conduction (for example, with severe bradycardia, atrioventricular block II-III degree);
- volumetric maxillofacial operations, as well as with prolonged surgery (longer than 20 minutes);
- arterial hypotension;
- in children under four years of age (safety and effectiveness have not been studied).
It should also be noted that with extreme caution this drug is prescribed for pregnant women with preeclampsia, as well as bleeding in the last trimester.
The drug "Artikain": instructions for use in dentistry
Before the introduction of the drug in question, an aspiration test should always be performed. This is necessary in order to minimize the likelihood of intravascular administration of the drug.
According to experts, during the introduction of the medication in question, the pressure on the piston of the syringe must be adjusted depending on the sensitivity of the tissues. In this case, injecting the drug into the inflamed areas of the oral mucosa is highly not recommended. Eating after an injection is allowed only after a complete restoration of sensitivity.
In the process of conducting uncomplicated tooth extraction located on the upper jaw (if there is no inflammation), use 1.7 ml of solution (per tooth). If required, the patient is additionally administered 1-1.7 ml of the drug.
For anesthesia with suturing and palatal incisions to create a palatine depot, the patient is prescribed 0.1 ml of the drug.
When removing premolars located on the lower jaw (with an uncomplicated degree), an infiltration anesthesia is performed. At the same time, it gives the effect of conductive analgesia.
When turning teeth for crowns (except molars of the lower jaw) and preparation of cavities, vestibular injection is carried out in a dosage of 0.5-1.7 ml per tooth.
read more a single administration of the drug, its maximum dosage for adults is 4 mg / Ubistesin of body weight.
Side effects
How is the medicine "Artikain" tolerated by patients? Instructions for use (side effects of this medication will be presented right now) claims that this drug very rarely causes negative effects. Among them can be distinguished such as:
- stupor, dizziness, respiratory distress, transient visual disturbances, muscular tremor, muscular twitching, blurred vision (temporary);
- generalized convulsions, paresthesias, decreased blood pressure, hypesthesia, blindness, heart failure, double vision, shock;
- allergic reactions, nausea, angioedema, vomiting, swelling, flushing of the skin, inflammation of the oral mucosa, conjunctivitis, urticaria, rhinitis;
- swelling of the cheeks, upper or lower lip, swelling of the vocal cords with difficulty swallowing.
It should also be noted that sometimes with the wrong introduction of a local anesthetic, damage to the facial nerve is possible. This can lead to paralysis.
Drug overdose
What are the signs of an overdose when misusing the Artikain medication? Instructions for use indicate the following symptoms: loss of consciousness, dizziness, decreased blood pressure, stupor during administration or motor agitation, bradycardia.
To eliminate such conditions, you should urgently stop the injection and put the patient on the bed. He also needs to ensure free passability of the respiratory tract, to control heart contractions and the state of blood pressure.
Drug Interactions
Local anesthetics are able to enhance the effect Ubistesin medicines that inhibit the central nervous system.
With parallel use with the described drug, the following interaction is observed:
- with anticoagulants, the risk of bleeding and hemorrhage increases;
- with monoamine oxidase inhibitors, the risk of developing arterial hypotension is increased;
- the effect of muscle relaxants is enhanced and lengthened;
- with vasoconstrictors, the local anesthetic effect of articaine is enhanced and lengthened;
- with narcotic analgesics, respiratory depression intensifies and an additive effect develops;
- with cholinesterase inhibitors articaine metabolism decreases.
It should also be noted that the drug in question is Ubistesin with anti-asthenic drugs. In addition, when treating the injection site with disinfectant solutions that contain heavy metals, the risk of developing an adverse reaction in the form of edema and painful sensitivity increases.
Special information
The drug in question cannot be administered intravenously. It is also forbidden to inject into the inflamed area.
Open solution cartridges cannot be reused, including for other patients.