Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.
Keamotin is a drug made in Hong Kong. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Famotidine is a complete analogue of Keamotin. It has the same composition, dosage and methods of use. Also Famotidine has a lower cost compared to Keamotin.
To buy Keamotin, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Tell your doctor right away of any new symptoms that occur during or after treatment. headache; dizziness; or a seizure; confusion, hallucinations, agitation, lack of energy;
Warnings
To make sure this medicine is safe for you, tell your doctor or pharmacist if you have ever had:
- kidney disease;
- liver disease;
- cancer stomach; or
- long QT syndrome (in you or a family member).
Ask a doctor before using famotidine if you are pregnant or breast-feeding.
Interactions
Multivitamins/Minerals (with ADEK, Folate, Iron): Histamine H2 Receptor Antagonists may decrease the serum concentration of Multivitamins/Minerals (with ADEK, Folate, Iron). Specifically, the absorption of iron may be impaired by H2-antagonists. Monitor therapy
Pexidartinib: Histamine H2 Receptor Antagonists may decrease the serum concentration of Pexidartinib. Management: Administer pexidartinib 2 hours before or 10 hours after histamine H2 receptor antagonists. Consider therapy modification
Erlotinib: Histamine H2 Receptor Antagonists may decrease the serum concentration of Erlotinib. Management: Avoid H2-antagonists in patients receiving erlotinib when possible. If concomitant treatment cannot be avoided, erlotinib should be dosed once daily, 10 hours after and at least 2 hours before H2-antagonist dosing. Consider therapy modification
Food interaction
Limit caffeine intake.
Take without regard to meals, food may slightly increase the product's bioavailability.
Avoid alcohol.
Pregnancy
- Emergency contraceptive pills prevent pregnancy by preventing or delaying ovulation and they do not induce an abortion.
- Topical corticosteroids should not be used by pregnant women over large areas of the body, in large amounts, or for prolonged periods of time.
Overview
Famotidine tablets are packaged in a blister pack of 10 pieces. A cardboard pack contains 2 or 3 blisters with tablets, as well as instructions for the use of the drug.
Therapeutic effects, pharmacokinetics
The main active ingredient of Famotidine tablets blocks histamine N2-gastric mucosa prescribe. This leads to a suppression of the intensity of the synthesis of hydrochloric acid and the enzyme pepsin of gastric juice. Reducing acidity is the main factor that allows to reduce the damaging effect of hydrochloric acid on the mucous membrane, especially in the case of the development of its defect in the form of an ulcer or erosion. After taking Famotidine tablets inside, the active substance is not completely absorbed into the systemic circulation (bioavailability is 45-50%). It is evenly distributed in the tissues of the body, metabolized in the liver with the formation of inactive decay products that are excreted from the body with urine.
Indications for use
Taking Famotidine tablets is indicated to reduce the acidity of gastric juice in various pathologies, accompanied by an increase in its functional activity:
- Peptic ulcer with violation of the integrity of the mucous membrane of the stomach or duodenum.
- Erosive gastroduodenitis - inflammation characterized by the formation of erosion.
- Symptomatic or stressful ulcers of the gastric mucosa.
- Reflux esophagitis - inflammation of the esophagus due to reverse reflux of gastric contents.
- Zolinger-Ellison syndrome is a pathological process characterized by the formation of a gastrin-producing tumor in the pancreas, which leads to an increase in the functional activity of the stomach.
- Prevention of complications associated with damage to the gastric mucosa provoked by taking drugs of the pharmacological group non-steroidal anti-inflammatory drugs.
- Systemic mastocytosis is https://zentherapycenter.com/let-o/ozidal.php chronic pathology accompanied by monocyte infiltration in the skin and in the internal organs, including the stomach.
- Polyendocrine adenomatosis - a disease accompanied by damage to most of the various glands of the stomach.
- Prevention of the development of gastrointestinal bleeding after surgery on the digestive tract.
- Dyspeptic syndrome, accompanied by heartburn and discomfort in the epigastrium and behind the sternum.
The drug is also used to prevent aspiration pneumonitis (pneumonia caused by the ingestion of acidic contents of the stomach into the respiratory tract), in particular after general anesthesia.
Contraindications
Under certain pathological and physiological conditions of the patient's body, taking Famotidine tablets is contraindicated, these include:
- Pregnancy at any stage of the course.
- Lactation (Breastfeeding).
- Patient age up to 3 years or body weight up to 20 kg.
- Individual intolerance Keamotin famotidine or auxiliary components of the drug.
With caution, this medication is used for hepatic, renal failure, liver cirrhosis (replacement of cells with connective additionally with a marked decrease in the functional activity of the organ), a decrease in the functional activity of the immune system. Before taking Famotidine tablets, it is important to exclude contraindications in the patient.
Proper use, dosage
Famotidine tablets are intended for oral administration. They are taken whole, not chewed and washed down with a sufficient amount of water. Dosage and mode of use depend on the indications:
- Peptic ulcer, including its exacerbation, this drug ulcers, erosive gastroduodenitis - 20 mg 2 times a day or 40 mg 1 time per day. If necessary, the daily dosage can be increased to 80-160 mg per day. The duration of the course of therapy is a period of time from 4 to 8 weeks.
- Dyspepsia due to increased functional activity of the stomach - 20 mg 1-2 times a day.
- Prevention of exacerbation of peptic ulcer - 20 mg once a day, usually at night before bedtime.
- Reflux esophagitis - 20-40 mg 2 times a day for a period of time from six months to 1 year.
- Zolinger-Ellison Syndrome - The initial dosage is 20 mg every 6 hours. If necessary, it gradually increases to 160 mg every 6 choice
- Prevention of aspiration of gastric juice into the respiratory tract, especially after general anesthesia - 40 mg on the eve of the proposed surgical intervention (morning or evening).
For children older than 3 years, the recommended therapeutic dosage is no more than 20 mg 2 times a day (daily dose should not exceed 40 mg). With concomitant moderate renal failure, the daily dosage of the drug is reduced to 20 mg.
Side effects
On the background of taking Famotidine tablets, side effects from various organs and systems may develop:
- Nervous system - dizziness, headache, sleep disturbance (insomnia), anxiety, tinnitus, depression (prolonged and pronounced decrease in mood), confusion, hallucinations, nervousness, psychosis, blurred vision, increased fatigue.
- Digestive system - nausea, accompanied by periodic vomiting, dry mouth, abdominal pain, stool disorders (constipation or diarrhea), bloating (flatulence), inflammation of the liver (hepatitis), pancreas (pancreatitis), increased liver transaminase enzymes in the blood indicating damage to hepatocytes.
- Cardiovascular Keamotin - reducing the heart rate (bradycardia), changing the rhythm of heart contractions (arrhythmia), lowering the level of systemic blood pressure (arterial hypotension), blocking conduction of an impulse through the atrioventricular node (atrioventricular block), vascular inflammation (vasculitis).
- Blood and red bone marrow - a decrease in the number of platelets (thrombocytopenia), granulocytes (agranulocytosis), all blood cells (pancytopenia).
- Skin and its appendages - hair loss (alopecia), the appearance of blackheads.
- Allergic reactions - a skin rash, itching, characteristic changes resembling a nettle burn (urticaria), bronchospasm with the development of an attack of shortness of breath (bronchospasm), severe swelling of the soft tissues of the face and external genital organs (angioedema Quincke), a systemic reaction with a critical a decrease in systemic blood pressure and multiple organ failure (anaphylactic shock).
- The reproductive system - a decrease in sexual desire for the opposite sex (decreased libido), an increase in the level of the prolactin enzyme in the blood in women, especially when taking large doses of the drug, an increase in the mammary glands in men (gynecomastia), and a lack of menstruation (amenorrhea) in women.
- Musculoskeletal system - pain in the muscles (myalgia) and joints (arthralgia).
The appearance of signs of the development of negative pathological reactions while taking Famotidine tablets is the reason for stopping the drug and going to the doctor.
Features of use
Before prescribing Famotidine tablets, the doctor must read the instructions for the drug and draw attention to several features of its proper use:
- Before starting the natural of this drug, it is important to exclude the development of a patient with a malignant pathology of the stomach or duodenum, since Famotidine tablets can mask the clinical picture, which will complicate the diagnostic process.
- Symptoms of peptic ulcer may disappear within 1-2 weeks after the start of the drug. Drug withdrawal is carried out only after instrumental confirmation of ulceration or erosion.
- It is recommended to cancel the drug gradually. This will avoid the development of the "rebound" syndrome, accompanied by increased symptoms of increased acidity of the stomach.
- In the case of the use of ketoconazole or itraconazole preparations, they should be taken 2 hours before taking Famotidine tablets to prevent deterioration in the absorption of active ingredients.
- In weakened patients, in particular, against the Keamotin of a decrease in the functional activity of the stomach, the use of the drug can lead to the spread of the infectious process in the gastric mucosa.
- Famotidine tablets suppress the skin's response to histamine, therefore, they can lead to false-negative results of skin allergy tests.
- During the course of treatment with the drug, it is important to avoid taking foods and drinks that have an irritating effect on the stomach.
- Patients with a concomitant burn may need an increase in the dose of the drug.
- The therapeutic effect of the drug is reduced in smokers.
- If a dose was missed, then it should be taken as soon as possible, without doubling.
- The active substance of the drug can interact with drugs of other pharmacological groups, therefore, their doctor should be warned about their possible use.
Keamotin the drug can lead to the development of adverse reactions from the nervous system, against the background of https://zentherapycenter.com/let-i/irinotecan-jv-healthcare.php use, it is not recommended to perform work associated with the need for an increased concentration of attention and speed of psychomotor reactions.
In the pharmacy network, Famotidine tablets are prescription. Their independent use is not recommended, as this can provoke the development of complications with consequences for health.
Overdose