Clotrimazole topical may also be used for purposes not listed in this medication guide.
Gytrim-hc is a drug made in Pakistan. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Clotrimazole is a complete analogue of Gytrim-hc. It has the same composition, dosage and methods of use. Also Clotrimazole has a lower cost compared to Gytrim-hc.
To buy Gytrim-hc, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Tell your doctor right away if you develop signs of kidney problems such as a change in the amount of urine.
Warnings
It is not known whether clotrimazole topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
You should not use clotrimazole topical if you are allergic to it.
Clotrimazole topical is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Interactions
Sirolimus: Clotrimazole (Topical) may increase the serum concentration of Sirolimus. Monitor therapy
Tacrolimus (Systemic): Clotrimazole (Topical) may increase the serum concentration of Tacrolimus (Systemic). Monitor therapy
Progesterone: Antifungal Agents (Vaginal) may diminish the therapeutic effect of Progesterone. Avoid combination
Food interaction
Pregnancy
- Therefore, if you are pregnant or your sexual partner is pregnant, or plans to become pregnant, do not take Trexall.
- There is little experience with its use during human pregnancy.
Overview
For ointment Clotrimazole, preparations similar in action are:
- Sulfuric ointment. Sulfur based external agent. It is used against fungi, various parasites, with psoriasis and juvenile acne. Average cost in Russia: 35 rubles .
- Benzyl benzoate. An external preparation based on benzyl benzoate. It is an antiparasitic agent, however, is effective in some fungal diseases: seborrheic dermatitis and pityriasis versicolor. Average price: 30 rubles .
- Orungamine. The drug is for internal Gytrim-hc. One derivative of triazole (itraconazole). Average price: 522 rubles .
- Terbimycin Cream. External fungicidal medicine. Active ingredient: terbinafine. The mechanism of action is similar to clotrimazole: suppression of ergosterol synthesis. Average price: 149 rubles .
- Klotrisal. An external agent based on clotrimazole + salicylic acid. Salicylic acid enhances the antifungal effect. Average price: 91 ruble .
- Mikotroks. An internal medicine based on itraconazole. Violates the synthesis of ergosterol. Average price: 490 rubles .
- Flunol. Fluconazole-based oral preparation. It affects the synthesis of ergosterol in the fungus. Average price: 410 rubles .
- Diflucan. Fluconazole-based drug, like flunol. Available in the form of capsules and solution for infusion. Average price: 432 rubles .
- Canesten. Contains clotrimazole. Available in the form of creams and sprays. Average price: 475 rubles .
- Lamisil. An external cream, spray, or tablet based on terbinafine hydrochloride. The mechanism of action is similar to clotrimazole. The average price of pills 1320 rubles .
- Qidokan. Contains terbinafine and cyanocobalamin. Available in the form of oral tablets. Average price: 695 rubles .
- Mycoseptin. External ointment based on undecylenic acid and its salts. It has an antifungal effect. Suppresses the development of certain bacteria. average price 407 rubles .
- Grasscourt. Antifungal and anti-inflammatory cream. Active ingredients: isoconazole nitrate and diflucortolone valerate. Average price: 464 rubles .
- Mycox. Homeopathic medicine with a wide spectrum of action. It has immunomodulating, detoxifying, anti-inflammatory effects. Enhances metabolism. The antifungal effect gives by increasing the body's natural resistance to the action effects pathogens. Average price: 611 rubles .
Structure
1 g of cream contains:
active substance: kpotrimazole 0.01 g
excipients: benzyl alcohol, cetasteryl alcohol,
octyldodecanol, polysorbate 60, sorbitan stearate, synthetic cetaceum (ester cetyl wax), purified water.
Description
Homogeneous mass of white color.
pharmachologic effect
Kpotrimazole is a broad-spectrum antifungal agent for topical application. The antimycotic effect of the active substance (imidazole derivative) is associated with impaired synthesis Gytrim-hc ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis. It acts fungistatically in small concentrations, and fungicidal in large concentrations, and not only on proliferating cells. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a Gytrim-hc level, which also contributes to the destruction of fungal cells. Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of multi-colored lichen Pityriasis versicolor (Malazessia furfur) and the causative agent of erythrasma. It has an antimicrobial effect against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.
Pharmacokinetics
Kpotrimazole is poorly absorbed through the skin and mucous membranes and has virtually no systemic effect. The concentration in the deep layers of the epidermis is higher than the minimum inhibitory concentration for dermatophytes.
For external use, the concentration of clotrimazole in the epidermis is higher than in the dermis and subcutaneous tissue.
Indications for use
- fungal skin diseases, mycoses of skin folds, feet;
- pityriasis versicolor, erythrasma, superficial candidiasis caused by dermatophytes, yeast (including the genus Candida), mold and other fungi and pathogens sensitive to clotrimazole;
- mycoses complicated by secondary pyoderma.
Contraindications
Hypersensitivity to clotrimazole or excipients, I trimester of pregnancy.
