Glimepiride may also be used for purposes not listed in this medication guide.
Glyset is a drug made in Pakistan. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Glimepiride is a complete analogue of Glyset. It has the same composition, dosage and methods of use. Also Glimepiride has a lower cost compared to Glyset.
To buy Glyset, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Check with your physician for additional information about side effects. fatigue or tiredness extreme fatigue lack of coordination headaches the condition being treated tingling or numbness in your lips or tongue hives enalaprilat
Warnings
Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.
Interactions
Dabrafenib: May decrease the serum concentration of CYP2C9 Substrates (High risk with Inducers). Management: Seek alternatives to the CYP2C9 substrate when possible. If concomitant therapy cannot be avoided, monitor clinical effects of the substrate closely (particularly therapeutic effects). Consider therapy modification
RaNITIdine: May increase the serum concentration of Sulfonylureas. Monitor therapy
Mecamylamine: Sulfonamides may enhance the adverse/toxic effect of Mecamylamine. Avoid combination
Food interaction
Even though food reduces product absorption, the manufacturer recommends taking the product with the first meal of the day.
Avoid alcohol.
Pregnancy
- Preeclampsia is a condition in pregnant women marked by high blood pressure and a high level of protein in the urine.
- If you miss pills at any time the risk of becoming pregnant increases.
Overview
A characteristic feature of non-insulin-dependent diabetes is hyperglycemia - a steady increase in blood serum sugar. Compliance with a diet that reduces the intake of carbohydrates, medical loss and the use of special medications can normalize the level of sugar in the body. One such drug is Glimepiride. An analogue of this agent should contain the same active substance or another compound, but having a similar effect.
What does the drug contain??
One of the drugs prescribed in the treatment of non-insulin-dependent diabetes mellitus is Glimepiride. The composition of this medicine is quite simple - there is only one active component in it, by the name of which the drug itself is named. This glimepiride is a third generation sulfonylurea. But what is it? Sulfonylurea refers to synthetic substances that have a sugar-lowering property. Scientists are constantly looking for new tools that can improve the well-being of patients, and sulfonylurea has already given people several of these discoveries.
More than a quarter of a century ago, German scientists proposed the use of glimepiride in the treatment of type 2 diabetes mellitus, the composition of which is based on sulfonylurea and is its third-generation derivative. The preparation also contains form-forming components:
- sodium carboxymethyl starch;
- lactose monohydrate;
- magnesium stearate;
- povidone;
- polysorbate;
- microcrystalline cellulose.
Among other things, microcrystalline cellulose helps the body in removing unnecessary substances from the intestine, being a natural sorbent and essential fiber for digestion. The antidiabetic drug Glimepiride, the manufacturer of which may be different, will contain one active substance with the same name and some additional components.
How does Glimepiride work??
One of the latest findings by pharmacologists in the fight against non-insulin-dependent diabetes is Glimepiride. Instructions for use of this drug indicate its effectiveness. Glimepiride, being a derivative of 3 generations of sulfonylurea, in the course of chemical reactions in the body during operation turns into two components - hydroxymetabolite and carboxymethabolite. Moreover, the first of the metabolites is a pharmacologically active substance - as a peripheral vasodilator lowers blood pressure.
What is the effect of "glimepiride"?
The drug "Glimepiride" receives mostly positive reviews, helping patients with non-insulin-dependent diabetes to fight the disease. This is due to the fact Glyset the active substance - glimepiride - makes the cells of the pancreas actively deliver insulin to the Oral. The goal of the treatment of type 2 diabetes is the normalization of carbohydrate metabolism. This is what glimepiride does.
Another function, albeit not the main one, of this medicinal substance is to reduce the production of glucose by the liver. And since the amount of glucose in the blood is not associated with the activity of sulfonylurea derivatives of 1, 2 or 3 generations, when taking such drugs hypoglycemia is possible - lowering blood sugar levels below the permissible level. With respect to glimepiride, the onset of a critical level of hypoglycemia for almost three decades of clinical observations on the use of this drug has not been recorded. This suggests that the drug is actively working without causing pathologies of carbohydrate metabolism. The active substance, which is called glimepiride, is the active ingredient in many drugs to combat type 2 diabetes.
The drug of the same name "Glimepiride", its analogue must contain the same active substance, or a substance of a similar action, helps to normalize the metabolism and metabolism of carbohydrates in the body, allowing you to lower blood sugar.
How to take the medicine?
A widely used drug in the treatment of non-insulin-dependent diabetes is Glimepiride. The dosage of a substance working in a medicinal product may vary - from 1, 2, 3, 4, 6 mg per unit dosage form. The drug is available in tablets, which is convenient for use by the patient. Moreover, the drug "Glimepiride", its analogue with the same active component, should be taken only once https://zentherapycenter.com/let-p/propofol-lipuro-1.php day, which is also convenient.
The amount of active substance necessary for daily use is prescribed by the doctor on the basis of regular monitoring of blood sugar and urine. This medication is usually started with a dosage of 1 mg. If necessary, increase the dose gradually, over 10-14 days, to 6 mg per day. It should be noted that the use of glimepiride more than 8 mg at a time is contraindicated. It is not advisable to break the dose into several doses, as the studies revealed the lack of a Kerron effect from repeated use of glimepiride per day.
When to not accept
Glimepiride tablets help patients with non-insulin-dependent diabetes if dietary adjustments and weight loss do not have an effect on normalizing blood sugar and urine levels. But taking this and similar drugs is necessary only as directed by the attending physician. The medicine "Glimepiride", its analogue with the same active component can not be taken in the following cases:
- insulin-dependent diabetes mellitus (type 1) - the absolute inefficiency of glimepiride;
- renal failure;
- liver failure;
- ketoacidosis - a metabolic shift in the acid-base balance of the body with increased acidity;
- coma;
- precoma;
- hypersensitivity to the components of the drug, including sulfonamides.
This drug is not prescribed for use during pregnancy or breastfeeding. The fact that the active substance crosses the placental barrier and into breast milk, says the instructions for use with the drug "Glimepiride".
Side effect
The 3rd generation sulfonylurea derivative - glimepiride, an analogue of the drug of the same name, helps to combat the insufficient sensitivity of the body's cells to insulin, normalizing the level of sugar. But the use of such medications can cause the following side effects:
- allergic reactions;
- abdominal pain (in the stomach);
- hypoglycemia;
- hyponatremia;
- leukopenia;
- violation of taste sensations - metallic taste in the mouth;
- impaired liver and / or kidney function;
- hypersensitivity to alcohol;
- nausea;
- weight gain;
- photodermatosis.