Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Glucovance is a drug made in Argentina, Australia, Brazil, Chile, Colombia, Croatia (Hrvatska), Cyprus, Ecuador, Egypt, France, Georgia, Hong Kong, Indonesia, Lebanon, Malaysia, Mexico, Netherlands, Oman, Pakistan, Peru, Philippines, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, South Africa, South Korea, Taiwan, Tunisia, Turkey, Venezuela, Vietnam. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Metformin is a complete analogue of Glucovance. It has the same composition, dosage and methods of use. Also Metformin has a lower cost compared to Glucovance.
To buy Glucovance, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Tell your doctor about any unusual or bothersome side effect. neuropathy, or nerve damage, which can lead to problems throughout the body, including the feet rash depression flushing slight weight loss being overweight or obese shortness of breath loss of strength
Warnings
You should not breastfeed while using this medicine.
You should not use metformin if you are allergic to it, or if you have:
- severe kidney disease; or
- metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).
If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking metformin. Be sure your caregivers know ahead of time that you are using this medication.
Metformin should not be given to a child younger than 10 years old. Some forms of metformin are not approved for use by anyone younger than 18 years old.
Interactions
Ombitasvir, Paritaprevir, and Ritonavir: May enhance the adverse/toxic effect of MetFORMIN. Specifically, the risk for lactic acidosis may be increased. Monitor therapy
Erdafitinib: May increase the serum concentration of OCT2 Substrates. Monitor therapy
Selective Serotonin Reuptake Inhibitors: May enhance the hypoglycemic effect of Blood Glucose Lowering Agents. Monitor therapy
Food interaction
Take with food to reduce gastric irritation.
Avoid alcohol.
Pregnancy
- Pregnant women should be encouraged to quit smoking without the use of pharmacotherapy.
- This medication is not recommended for use during pregnancy.
- You and your doctor should discuss whether you should continue to take this medicine during pregnancy.
Overview
Indications for use
This medication is on allow list of vital medicines approved by WHO (World Health Organization). Metformin is prescribed in such conditions as:
Glucovance 2 diabetes mellitus (insulin dependence). Statistics on the use of the drug fixes a 30% reduction in patient mortality in comparison with other drugs prescribed for diabetes. Positive dynamics is observed in all patients, especially in overweight patients. - Prediabetes (increased risk of diabetes).
- Polycystic ovary syndrome. The medicine began to be used to treat PCOS at the turn of the 80-90s of the twentieth century. A connection was found between this pathology and insulin hypersecretion, a violation of the metabolic response of tissues to insulin during a normal reaction to this ovarian hormone. When dimethylbiguanide is included in the complex of medicines, 80% of women diagnosed with polycystosis have a positive dynamics.
- Obesity treatment.
- Metabolic syndrome.
How to take
The tablets are swallowed whole, washed down with plenty of water. The initial minimum dose is 500 mg once a day, the maximum is 2.5-3 g. It effectiveness recommended to take metformin tablets after dinner or immediately before bedtime. The dosage of the drug is better to increase gradually. A large initial dose of dimethylbiguanide causes stomach dysfunction and disrupts the digestive process. Metallic aftertaste, nausea - signs of an overdose at the initial stages of the use of pharmaceuticals.
With monotherapy with a drug, it is better to adhere to a proven scheme:
- In more first week, a medicine in an amount of 500 mg is taken 1 time.
- Next, the daily dose is increased to 850-1000 mg and divided into 2 doses.
- If the metabolic processes are unsatisfactory at a maximum dose of 2000 mg, sulfonylureas should be added to metformin or insulin should be used.
- An increase in dosage depends on glucose readings. The regimen is selected by the doctor individually.
- In elderly patients, the maximum daily dose is 1000 mg.
With diabetes, patients have to take many different drugs. One of the most important means is sugar-lowering pills, which the doctor selects.
Metformin - description and action
Metformin Tablets (500.850 mg) sold in all pharmacies, this is a drug with hypoglycemic effect for oral administration. It is prescribed for patients with type 2 diabetes and for a number of other indications. The main active substance is metformin, additional substances:
The medicine is sold in blisters for 30-120 pieces, the price for 30 tablets is about 120 rubles. The drug is produced by various manufacturers - "Gideon Richter","Teva","Canon","Biotech", Etc. Metformin show to the Glucovance of biguanides, its effect is based on a decrease in gluconeogenesis in the liver, as a result of which the absorption of sugar from the small intestine decreases.
