Overview
Carefully: bronchial asthma, intolerance to seafood (shrimp, shellfish), diabetes.
Pregnancy and lactation
Studies on the efficacy and safety Baladene glucosamine use in pregnant and lactating women have not been conducted, and therefore taking the drug is not recommended for women during pregnancy and lactation.
Dosage and administration
Inside, one packet once a day, preferably with meals. The contents of one packet should be dissolved in a glass of water.
The duration of treatment is usually 4-6 weeks. The treatment courses are repeated if necessary with an interval of 2 months.
Glucosamine is not intended to treat acute pain symptoms. Relief of symptoms (especially pain relief) can occur only after several weeks of use, and sometimes longer. RWR symptom relief does not occur after 2–3 months, continued Glucosamine with glucosamine should be reviewed.
Dosage adjustment in elderly patients is not required.
Patients with impaired renal and / or horse function
Studies of glucosamine use in patients with impaired renal and / or liver function have not been conducted, therefore, there are no dosage recommendations for such patients.
Side effect
The incidence of side effects is given in Glucosamine following gradation: very often (≥1 / 10); often (≥1 / 100,
Overdose
Interaction with other drugs
Special studies of the interaction of glucosamine with other drugs have not been conducted. Given the physicochemical and pharmacokinetic properties of glucosamine, the likelihood of interaction is low. However, the interaction cannot be completely excluded, therefore, glucosamine should be used in combination with other drugs with caution.
There are reports use drug when glucosamine was used in combination for the anticoagulants of the coumarin group (warfarin, acenocoumarol), an increase in prothrombin time was observed. At the beginning of treatment or after treatment with glucosamine, patients using coumarin anticoagulants should be carefully monitored.
When combined, glucosamine enhances the absorption of tetracyclines and reduces penicillins and chloramphenicol.
The drug is compatible with non-steroidal anti-inflammatory drugs and glucocorticosteroids. When combined with non-steroidal anti-inflammatory drugs, it enhances the anti-inflammatory and analgesic effect of the latter.
Precautionary measures
Before starting the use of glucosamine, it is necessary to establish whether the above symptoms are caused by the primary disease, which must be treated with specific agents.
After taking glucosamine, asthma symptoms may worsen, therefore, patients with bronchial asthma should take glucosamine with caution and carefully monitor, especially at the beginning of treatment. Asthma patients should be warned before taking glucosamine that asthma symptoms may worsen.
Glucosamine should be used with caution in patients with diabetes.
Patients diagnosed with impaired glucose tolerance need to measure the concentration of glucose in the blood before treatment, as well as regularly during treatment and, if necessary, change the dose of insulin.
RWR to the content of aspartame, it is contraindicated in patients with phenylketonuria.
The drug contains sorbitol, which must be taken into account for patients with rare congenital fructose intolerance.
Sorbitol, which is part of the drug, can cause osmotic diarrhea.
Glucosamine can sometimes contribute to hypercholesterolemia, therefore it is recommended to control lipid metabolism.
Special studies in patients horse from impaired renal and / or liver function have not been conducted. According to toxicological and pharmacokinetic studies of glucosamine, such patients should not limit the dose. Caution is advised in patients with severe renal or hepatic insufficiency.
