Glimepiride is an oral diabetes medicine that is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. glimepiride is not for treating type 1 diabetes.
Glimepiride Aurobindo is a drug made in Malta, Netherlands, Poland. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Glimepiride is a complete analogue of Glimepiride Aurobindo. It has the same composition, dosage and methods of use. Also Glimepiride has a lower cost compared to Glimepiride Aurobindo.
To buy Glimepiride Aurobindo, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Consult your doctor or pharmacist for more information. cuts or bruises that are slow to heal hives weakness or fatigue sweating the condition being treated tingling, pain, or numbness in your hands or feet aspirin sweating
Warnings
If you breastfeed while taking glimepiride, call your doctor if your baby shows signs of hypoglycemia (extreme drowsiness, feeding problems, mottled skin, blue lips, feeling cold or jittery, or having a seizure).
Interactions
Maitake: May enhance the hypoglycemic effect of Blood Glucose Lowering Agents. Monitor therapy
Antidiabetic Agents: May enhance the hypoglycemic effect of Hypoglycemia-Associated Agents. Monitor therapy
Dexketoprofen: May enhance the adverse/toxic effect of Sulfonamides. Monitor therapy
Food interaction
Even though food reduces product absorption, the manufacturer recommends taking the product with the first meal of the day.
Avoid alcohol.
Pregnancy
- Drug interactions, dosage, and pregnancy and breastfeeding safety information, and dosing should be reviewed before taking any medication.
- It should not be used in pregnant women unless the potential benefits to the mother outweigh any risks to the developing baby.
- The are no adequate studies in pregnant women.
Overview
What does the drug contain??
One of the drugs prescribed in the treatment of non-insulin-dependent diabetes mellitus is Glimepiride. The composition of this medicine is quite simple - there is only one active component in it, by the name of which the drug itself is named. This glimepiride is a third generation sulfonylurea. But what is it? Sulfonylurea refers to synthetic substances that have Glimepiride sugar-lowering property. Scientists are constantly looking for new tools that can Aurobindo the well-being of patients, and sulfonylurea has already given people several of these discoveries.
More than a quarter of a century ago, German scientists proposed the use of glimepiride in the treatment of type 2 diabetes mellitus, the composition of which is based on sulfonylurea and is its third-generation derivative. The preparation also contains form-forming components:
- sodium carboxymethyl starch;
- lactose monohydrate;
- magnesium stearate;
- povidone;
- polysorbate;
- microcrystalline cellulose.
Among other things, microcrystalline cellulose helps the body in removing unnecessary substances from the intestine, being a natural sorbent and essential fiber for digestion. The antidiabetic drug Glimepiride, the manufacturer of which may be different, will contain one active substance with the same name and some additional components.
How does Glimepiride work??
One of the latest findings by pharmacologists in the fight against non-insulin-dependent diabetes is Glimepiride. Instructions for use active ingredient this drug indicate Aurobindo effectiveness. Glimepiride, being a derivative of this page generations of sulfonylurea, in the course of chemical reactions in the body during operation turns into two components - hydroxymetabolite and carboxymethabolite. Moreover, the first of the metabolites is a pharmacologically active substance - as a peripheral vasodilator lowers blood pressure.
What is the effect of "glimepiride"?
The drug "Glimepiride" receives mostly positive reviews, helping patients with non-insulin-dependent diabetes to fight the disease. This is due to the fact that the active substance - glimepiride - makes the cells of the pancreas actively deliver insulin to the body. The goal of the treatment of type 2 diabetes is the normalization of carbohydrate metabolism. This is what glimepiride does.
Another function, albeit not the main one, of this medicinal substance is to reduce the production of glucose by the liver. And since the amount of glucose in the blood is not associated with the activity of sulfonylurea derivatives of 1, 2 or 3 generations, when taking such drugs hypoglycemia is possible - lowering blood sugar levels below the permissible level. With respect to glimepiride, the onset of a critical level of hypoglycemia for almost three decades of clinical observations on the use of this drug has not been recorded. This suggests that the drug is actively working without causing pathologies of carbohydrate metabolism. The active substance, which is called glimepiride, is the active ingredient in many drugs to combat type 2 diabetes.
The drug of the same name "Glimepiride", its analogue must contain the same active substance, or a substance of a similar action, helps to normalize the metabolism and metabolism of carbohydrates in the body, allowing you to lower blood sugar.
How to take the medicine?
A widely used drug in the treatment of non-insulin-dependent diabetes is Glimepiride. The dosage of a substance working in a medicinal product may vary - from 1, 2, 3, 4, 6 mg per unit dosage form. The drug is available in tablets, which is convenient for use by the patient. Moreover, the drug "Glimepiride", its analogue with the same active component, should be taken only once a day, which is also convenient.
The amount of active substance necessary for daily use is prescribed by the doctor on the basis of regular monitoring of blood sugar and urine. This medication is usually started with a dosage of 1 mg. If necessary, increase the dose gradually, over 10-14 days, to 6 mg per day. It should be noted that the use of glimepiride more than 8 mg at a time is contraindicated. It is not advisable to break the dose into several doses, as the studies revealed the lack of a therapeutic Glimepiride from repeated use of glimepiride per day.
When to not accept
Glimepiride tablets help patients fact that non-insulin-dependent diabetes if dietary adjustments and weight loss do not have an effect on normalizing blood sugar and urine levels. But taking this and similar drugs is necessary only as directed by the attending physician. The medicine "Glimepiride", its analogue with the same active component can not be taken in the following cases:
- insulin-dependent diabetes mellitus (type 1) - the absolute inefficiency of glimepiride;
- renal failure;
- liver failure;
- ketoacidosis - a metabolic shift in the acid-base balance of the body with increased acidity;
- coma;
- precoma;
- hypersensitivity to the components of the drug, including sulfonamides.
This drug is not prescribed for use during pregnancy or breastfeeding. The fact that the active substance crosses the placental barrier and into breast milk, says the instructions for use with the drug "Glimepiride".
Side effect
The 3rd generation sulfonylurea derivative - glimepiride, an analogue of the drug of the same name, helps to combat the insufficient sensitivity of the body's cells to insulin, normalizing the level of sugar. But the use of such medications can cause the following side effects:
- allergic reactions;
- abdominal pain (in the stomach);
- hypoglycemia;
- hyponatremia;
- leukopenia;
- violation of taste sensations - metallic taste in the mouth;
- impaired liver and / or kidney function;
- hypersensitivity to alcohol;
- nausea;
- weight gain;
- photodermatosis.
The appearance of such reactions to the use of drugs with the active active component glimepiride requires consulting a doctor, adjusting the dosage of the drug, or changing the drug substance to another.
Similar drugs
In a non-insulin-dependent diabetic clinic, the drug Glimepiride is widely used. The analogue of this medication should contain the same active substance - glimepiride, a sulfonylurea derivative. Such drugs in the pharmacy market are a sufficient choice - Amaril, Diamerid, Glimaz, Meglimid and some others.
