Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.
Geroquel is a drug made in Ireland. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Quetiapine is a complete analogue of Geroquel. It has the same composition, dosage and methods of use. Also Quetiapine has a lower cost compared to Geroquel.
To buy Geroquel, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Consult your doctor or pharmacist for more information. Abnormally Low Blood Pressure Inflammation Of The Nose Chronic Trouble Sleeping Drowsiness Shaking Extremities Head Pain Loss Of Appetite Intense Abdominal Pain
Warnings
Some people have thoughts about suicide while taking quetiapine. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
You should not use quetiapine if you are allergic to it.
Tell your doctor if you have ever had:
- liver disease;
- heart problems;
- high or low blood pressure;
- low white blood cell (WBC) counts;
- abnormal thyroid tests or prolactin levels;
- constipation or urination problems;
- an enlarged prostate;
- a seizure;
- glaucoma or cataracts;
- high cholesterol or triglycerides;
- diabetes (in you or a family member); or
- trouble swallowing.
Interactions
MetyroSINE: CNS Depressants may enhance the sedative effect of MetyroSINE. Monitor therapy
Nitroglycerin: Anticholinergic Agents may decrease the absorption of Nitroglycerin. Specifically, anticholinergic agents may decrease the dissolution of sublingual nitroglycerin tablets, possibly impairing or slowing nitroglycerin absorption. Monitor therapy
Chloral Betaine: May enhance the adverse/toxic effect of Anticholinergic Agents. Monitor therapy
Food interaction
Take without regard to meals.
Avoid alcohol.
Pregnancy
- There is no good way to tell if an unborn baby has been harmed.
- Tell your doctor if you are pregnant or plan on getting pregnant.
Overview
Dosage form
Film-coated sustained-release tablets, 50 mg, 200 mg, 300 mg or 400 mg
Structure
One tablet contains
active substance - quetiapine fumarate 57.5 mg, 230 mg, 345 mg and 460 mg (equivalent to quetiapine 50 mg, 200 mg, 300 mg and 400 mg),
Excipients: hypromellose Methocel E5 Premium, hypromellose Methocel K100 Premium LV, hypromellose Methocel K4M Premium CR, microcrystalline cellulose, sodium citrate anhydrous,
magnesium stearate, purified water,
Opadri 15V265003 Brown: titanium dioxide (E 171), hypromellose 3cP hypromellose 6cP, macrogol 400, iron oxide yellow (E 172), iron oxide red (E 172), black iron oxide (E 172), polysorbate 80 (for dosage of 50 mg ),
Opadri 15V220002 Yellow: titanium dioxide (E 171), hypromellose 3cP, hypromellose 15cP, macrogol 400, iron oxide yellow (E 172), iron oxide red (E 172), polysorbate 80 (for dosage 200 mg),
Opadri 115V220003 Yellow: titanium dioxide (E 171), hypromellose 3cP, hypromellose 6cP, macrogol 400, iron oxide yellow (E 172), iron oxide red (E 172), iron oxide black (E 172), polysorbate 80 (for dosage 300 mg),
Opadri YS-1-7003 White: titanium dioxide (E171), hypromellose 3cP, hypromellose 6cP, macrogol 400, polysorbate 80 (for dosage 400 mg)
Description
Brown film-coated tablets, oval, engraved with "Q50" on one side and smooth on the other side (for a dosage of 50 mg).
Yellow film-coated tablets, oval, engraved with "Q200" on one side and smooth on the other side (for a dosage of 200 mg).
Film tablets coated with a light yellow color, engraved with "Q300" on one side and smooth on the other side (for a dosage of 300 mg).
White film coated tablets, engraved with "Q400" on one side and smooth on the other side (for a dosage of 400 mg).
Farmacotherapeutic group
Psychotropic drugs. Antipsychotics (antipsychotics). Dibenzodiazepines and their derivatives. Quetiapine.
ATX Code N05AH04
Pharmacological properties
Pharmacokinetics
When administered orally, quetiapine is well absorbed and actively metabolized. Eating does not significantly affect the bioavailability of quetiapine. Quetiapine is approximately 83% bound to plasma proteins. Geroquel maximum molar concentration of the active metabolite of N-desalkyl-quetiapine in equilibrium is 35% of the noted concentrations for quetiapine. The half-lives of quetiapine and N-desalkyl-quetiapine are about 7 and 12 hours, respectively.
The pharmacokinetics of quetiapine and N-desalkyl-quetiapine in the approved dose range is linear. In men and women, the kinetics of quetiapine does not differ.
The average clearance of quetiapine in elderly patients is approximately 30–50% lower than in adult patients aged 18 to 65 years.
In subjects with severe impaired Geroquel function (creatinine clearance less than 30 ml / min / 1.73 m2), the average plasma clearance of quetiapine was reduced by about 25%, however, some indicators of clearance corresponded to the range for healthy subjects.
The average molar dose fraction of free quetiapine and the active metabolite N-desalkyl-quetiapine, which was excreted in the urine, was 10%)
