Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.
Celebrex is a drug made in Argentina, Australia, Belgium, Bosnia & Herzegowina, Canada, China, Colombia, Cyprus, Czech Republic, Ecuador, Egypt, Estonia, France, Georgia, Germany, Greece, Hong Kong, Indonesia, Ireland, Italy, Kuwait, Latvia, Lebanon, Lithuania, Macedonia, Malaysia, Malta, Mexico, Myanmar, Netherlands, Norway, Peru, Philippines, Poland, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, South Africa, South Korea, Spain, Taiwan, Thailand, Turkey, United Kingdom, United States, Venezuela, Vietnam. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Celecoxib is a complete analogue of Celebrex. It has the same composition, dosage and methods of use. Also Celecoxib has a lower cost compared to Celebrex.
To buy Celebrex, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Contact your doctor for further instructions if this occurs. respiratory tract infection Skin reactions, including rash or blisters ankylosing spondylitis unusual weight gain angiotensin II receptor blockers heartburn rheumatoid arthritis Skin reactions, including rash or blisters
Warnings
This medicine may affect fertility (ability to have children) in women. Ask your doctor about this risk.
Taking celecoxib during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Interactions
Sincalide: Drugs that Affect Gallbladder Function may diminish the therapeutic effect of Sincalide. Management: Consider discontinuing drugs that may affect gallbladder motility prior to the use of sincalide to stimulate gallbladder contraction. Consider therapy modification
Prilocaine: Methemoglobinemia Associated Agents may enhance the adverse/toxic effect of Prilocaine. Combinations of these agents may increase the likelihood of significant methemoglobinemia. Management: Monitor patients for signs of methemoglobinemia (e.g., hypoxia, cyanosis) when prilocaine is used in combination with other agents associated with development of methemoglobinemia. Avoid lidocaine/prilocaine in infants receiving such agents. Monitor therapy
Floctafenine: May enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents. Avoid combination
Food interaction
Taking this product with a high-fat meal will delay the Cmax, but total absorption will be increased by 10 to 20%.
Take without regard to meals.
Pregnancy
- If a pregnancy occurs while using the medicine, tell your doctor right away.
- There is also evidence that the addition of 200 mg of mifepristone to the induction protocol decreases the interval to delivery for termination of pregnancy.
- Diabetes is usually controlled using insulin during pregnancy, because this provides a more stable control of blood sugar.
Overview
Celecoxib is prohibited during gestation and lactation.
Contraindications
The medicine is prohibited with the following pathologies:
- hypersensitivity to celecoxib or additional substances that make up the capsules;
- intolerance to other sulfonamide derivatives;
- bronchial asthma, which can occur along with polyps of the nasal cavity and paranasal sinuses, intolerance to non-steroidal anti-inflammatory drugs, including aspirin;
- a history of coronary bypass surgery;
- inflammatory bowel disease in the acute stage (ulcerative colitis, transmural ileitis);
- severe hepatic and renal failure (with creatine clearance less than 30 ml / min);
- progressive kidney disease;
- low potassium in the blood;
- heart failure, coronary heart disease;
- hemorrhage in the subarachnoid space;
- hypertensive intracerebral hemorrhage;
- digestive tract bleeding;
Celebrex ulcer and 12 duodenal ulcer; - milk sugar intolerance, hypolactasia, malabsorption of monosaccharides in the intestine.
With caution, the medication should be drunk if the patient has the following violations:
- swelling
- tuberculosis;
- a history of liver disease, moderate liver failure;
- kidney pathology, in which creatine clearance of 30-60 ml / min;
- decrease in the volume of circulating blood;
- pathology of the cardiovascular system, including high pressure, high lipid content;
- diabetes;
- smoking;
- alcohol abuse;
- a history of digestive organs;
- Helicobacter pylori infection.
With caution, Celecoxib should be drunk for people with a slowed metabolism, elderly patients, including those undergoing treatment with diuretics, weakened patients with low body weight.
Dosage and Administration
for adults
Capsules must be swallowed, without violating their integrity, regardless of food intake,
For osteoarthritis and Strumpell-Ankylosing spondylitis-Marie’s disease, the medication is prescribed in a daily dosage of 200 mg. You can drink it for 1 or 2 times. In patients with ankylosing spondylitis, the daily dosage can be increased to 800 mg, which must be drunk 2 times.
With rheumatoid arthritis, the medication is prescribed in a single dosage of 100-200 mg, the Celebrex of administration 2 times a day.
For pain and algodismenorrhea, the medication is Celebrex in an initial dosage of 400 mg (with severe pain in the first day, you can take another 200 mg of the drug). Then the medicine is drunk 200 mg twice a day.
For patients weighing up to 50 kg, the drug is prescribed in the lowest effective dosage, patients with a slow metabolism, moderate liver failure, taking Fluconazole dosage of Celecoxib is recommended to be reduced by 2 times.
for children
Celecoxib is not used in pediatrics.
for pregnant and lactating
Celecoxib is not used to treat women in position and breastfeeding.
Side effects
The following side this page may occur during therapy:
- swelling of the arms and legs, the appearance or progression of arterial hypertension, arrhythmia, hot flashes, tachycardia, heart attack, stroke, congestive heart failure;
- abdominal pains, diarrhea, increased gas formation, vomiting, peptic ulcer, gastrointestinal bleeding, rupture of the walls of the digestive tract, impaired liver function;
- dizziness, hypertension, insomnia, drowsiness, impaired consciousness, serous meningitis, hallucinations;
- infectious and inflammatory diseases of the urinary tract, renal failure, tubulointerstitial nephritis;
- infections of the upper and lower respiratory tract, including sinusitis, bronchitis, pharyngitis;
- hematomas, anemia, decreased platelet count;
- flu-like syndrome;
- urticaria, cure, rash, photoallergy, skin peeling, Stevens-Johnson syndrome, Lyell syndrome,
- ringing in the ears, visual disturbances, smell, taste;
- allergy;
- menstrual dysfunction;
- accidental injuries.
Interaction with other drugs
Celecoxib blocks CYP2D6 isoenzymes, therefore, it affects drugs metabolized with their participation.