Nebivolol may also be used for purposes not listed in this medication guide.
Byvalson 5 mg/80 mg is a drug made in United States. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Nebivolol is a complete analogue of Byvalson 5 mg/80 mg. It has the same composition, dosage and methods of use. Also Nebivolol has a lower cost compared to Byvalson 5 mg/80 mg.
To buy Byvalson 5 mg/80 mg, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Get emergency medical help if you have even mild symptoms: unstable heart failure rash dizziness diarrhea Trouble breathing, or shortness of breath propranolol nausea swelling of your throat or tongue
Warnings
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether nebivolol will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.
Interactions
Reserpine: May enhance the hypotensive effect of Beta-Blockers. Monitor therapy
Pholcodine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Pholcodine. Monitor therapy
Epinephrine (Racemic): Beta-Blockers (Beta1 Selective) may diminish the therapeutic effect of Epinephrine (Racemic). Monitor therapy
Food interaction
Pregnancy
- Women who are pregnant or nursing should not use this drug since it has several side effects that, although rare, can be severe.
- Do not use this medication if you are in the third trimester of pregnancy.
- Tell your doctor right away if you become pregnant while taking this medication.
Overview
Dosage regimen
Tablets are taken orally, 1 time per day, preferably always at the same time of the day, regardless of food intake, with plenty of fluids.
The average daily dose for the treatment of arterial hypertension and ischemic heart disease is 2.5-5 mg (1 / 2-1 tablets). Nebilet® can be used in monotherapy or mg/80 combination with other drugs that lower blood pressure.
In patients with renal failure, as well as in patients over mg/80 age of 65, the initial dose is 2.5 mg (1/2 tablet) per day. If necessary, the daily dose can be increased to a maximum of 10 mg (2 tablets in 1 dose).
Treatment of chronic heart failure should begin with a slow dose increase until an individual optimal maintenance dose is reached. Dose selection Byvalson the beginning of treatment must be carried out while maintaining intervals of 1 to 2 weeks and based on patient tolerance of this dose: a dose of 1.25 mg of nebivolol (1/4 tablet) 1 time per day can be increased initially to 2.5-5 mg (1 / 2-1 tablet), and then - up to 10 mg (2 tablets) 1 time per day.
The maximum recommended dose is 10 mg once daily.
At the beginning of treatment Byvalson with each increase in dose, the patient should be under medical supervision for at least 2 hours to ensure that the clinical condition remains stable (especially blood pressure, heart rate, conduction disturbances, and symptoms of aggravation of the course of chronic heart failure).
Pill Division Rules
To divide, place the tablet on a hard, even surface with a cross-shaped notch up, press on the tablet with both index fingers. To get 1/4 tablet, repeat these steps with 1/2 tablet.
Side effect
The frequency of side effects: very often (> 10%), often (> 1% and 0.1% and 0.01% and
Price Nebivolol and the availability of pharmacies in the city
Attention! Above is a look-up table, information may have changed. Data on prices and availability change in real time in order to see them - you mg/80 use the search (always up-to-date information in the search), and also if you need to leave an order for a medicine, select areas of the city to search, or search only by open pharmacies.
The above list is updated at least every 6 hours (it was updated 04.10.2019 at 11:46 - Moscow time). Specify the prices and availability of drugs through a search (the search bar is located on the top), as well as by pharmacy phone numbers before visiting the pharmacy. The information contained on the site cannot be used as recommendations for self-medication. Before using medicines, be sure to consult your doctor.
Farm action
Cardioselective beta1-blocker; It has a hypotensive, antianginal and antiarrhythmic effect. Reduces elevated blood pressure at rest, with physical exertion and stress. Competitively and selectively blocks synaptic and mg/80 beta1-adrenergic receptors, making them inaccessible to catecholamines, modulates the release of endothelial vasodilating factor (NO). The antihypertensive effect is also due to a decrease in the activity of RAAS (it does not directly correlate with a change in plasma renin activity). In the first days of treatment, the OPSS increases, in the future, with prolonged use, it Byvalson or decreases. The antihypertensive effect occurs after 2-5 days, a stable fact that is observed after 1-2 months. Reducing myocardial oxygen demand (heart rate reduction and reduction of myocardial contractility), reduces the number and severity of angina attacks and increases exercise tolerance. By increasing the final diastolic pressure in the LV and increasing the stretching of the muscle fibers of the ventricles, it can increase the need for oxygen, especially in patients with heart failure. The antiarrhythmic effect is due to the suppression of the automatism of the heart (including in the pathological focus) and the slowdown of AV conduction.
Pharmacokinetics
After oral administration, absorption from the gastrointestinal tract is fast. Eating does not affect absorption. Bioavailability is 12% in individuals with a "fast" metabolism (first-pass effect) and almost complete in individuals with a "slow" metabolism. The connection with plasma proteins for D-nebivolol is 98.1%, for L-nebivolol - 97.9%. It is metabolized by alicyclic and aromatic hydroxylation and partial N-dealkylation; the resulting hydroxy and amino derivatives are conjugated with glucuronic acid and excreted as O- and N-glucuronides. T1 / 2 hydroxymetabolites - 24 hours, enantiomers of nebivolol - 10 hours (in individuals with a "fast" metabolism); hydroxymetabolites - 48 hours, enantiomers of nebivolol - 30-50 hours Byvalson individuals with a "slow" metabolism). It is excreted by the kidneys (38%), intestines (48%).
Indications
