Sulfadiazine is an antibiotic that fights bacteria.
Burnazin is a drug made in Indonesia, Pakistan. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Sulfadiazine is a complete analogue of Burnazin. It has the same composition, dosage and methods of use. Also Sulfadiazine has a lower cost compared to Burnazin.
To buy Burnazin, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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You can also use a coupon giving a 5% discount.
Side effects
Tell your doctor right away of any new symptoms that occur during or after treatment. low white blood cell count swelling in the kidney burning sensation adverse gastrointestinal effects toxic injury to the liver discontinued production of blood cells localized eruption of the skin No information available
Warnings
Do not use sulfadiazine during late pregnancy, just before you deliver.
Sulfadiazine can pass into breast milk and may harm a nursing baby. Do not breast-feed while using sulfadiazine.
To make sure sulfadiazine is safe for you, tell your doctor if you have:
- kidney disease;
- liver disease;
- asthma, severe allergies; or
- a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Interactions
Dexketoprofen: May enhance the adverse/toxic effect of Sulfonamides. Monitor therapy
Selective Serotonin Reuptake Inhibitors: May enhance the hypoglycemic effect of Blood Glucose Lowering Agents. Monitor therapy
Procaine: May diminish the therapeutic effect of Sulfonamide Antibiotics. Avoid combination
Food interaction
Pregnancy
- If you become pregnant, stop taking this medicine as soon as you find out and see your doctor immediately.
- The use of antiretroviral therapy during late pregnancy, intrapartum, and immediately postpartum prevents a high proportion of vertical transmission.
- The use of nifuroxazide, nifurtimox, local nitrofurans, methenamine, and nitroxoline should be avoided during pregnancy.
Overview
Enhances the side effects of anesthetics, amiodarone, sulfonylurea derivatives, anticoagulants, antimalarial and antiepileptic drugs, cyclosporine. May interfere with the bactericidal effect of penicillins information the treatment of meningitis or other diseases requiring a rapid bactericidal effect. It reduces the concentration of cyclosporine in plasma, enhancing its metabolism. Enhances the effects of methotrexate (displaces from protein binding sites). Cimetidine increases the risk of developing leukopenia. Myelotoxic drugs - the risk of leukemia and / or thrombocytopenia. Estrogen-containing oral contraceptives - an increase in the frequency of breakthrough bleeding and the onset of pregnancy. Hepatotoxic drugs - the risk of hepatotoxicity. Methenamine - the risk Burnazin crystalluria (with an acidic reaction of urine, methenamine turns into formaldehyde, which can form an insoluble precipitate with sulfadiazine). Sulfinpyrazone and phenylbutazone increase concentration due to displacement from protein binding sites.
Pharmacotherapeutic group D06BA01 - products for use in dermatology. Chemotherapeutic agents for topical application with SE S2 action. Sulfonamides.
The main pharmacological action: oligodynamic, bacteriostatic and bactericidal, has an antimicrobial effect on grams (+) and grams (-) bacteria and fungi (Candida, Phycomycetes and Aspergillus spp, dermatophytes) the activity of the drug is due to silver ions that are released in the wound as a result of moderate dissociation of silver sulfadiazine, which complements sulfadiazine (sulfanilamide) silver ions are adsorbed on the surface of microbial cells and provide oligodynamic bacteriostatic and bactericidal action.
INDICATIONS: Infected burns, pressure sores, BPF ulcers (recommendation for the use of drugs in the British National Formula, issue 60), WHO (recommendation for the use of drugs in the World Health Organization Basic Form “I, 2008”), superficial wounds with weak exudation, infection prevention burns, pressure sores, ulcers, superficial wounds, abrasions, as well as during transplantation of BNF skin (recommendation for the use of drugs in the British National Formulary, 60th issue).
Dosage and administration: after removal of including tissue, the ointment is applied with a thin layer (2-4 mm) on the damaged area 1 - 2 g / day (number of times per day), in a sterile et 'connection or in an open way, the treatment lasts up to 3 weeks.
Side effects when using drugs: short-term burning, pain, skin rash, burning, itching, redness, allergic rhinitis, or allergic AD (bronchial asthma) as a result of long-term treatment this medicine treatment of large areas of the skin, argyria may occur - as a result of the accumulation of silver in the tissues, present skin may become slightly grayish, nausea, vomiting, diarrhea, glossitis, joint pain, liver damage, headache, confusion, convulsive cramps, crystalluria, kidney damage, leukopenia, thrombocytopenia, eosinophilia.
Contraindications to the use of drugs: hypersensitivity to silver sulfadiazine, sulfonamides or to any component of the drug, a genetic deficiency of glucose-6-phosphate dehydrogenase; premature babies, newborns and children under 3 months of age (risk of nuclear jaundice), pregnancy and breastfeeding are not suitable for the treatment of deep purulent wounds and burn wounds with profuse exudation.
Forms of release of drugs: cream 1% by 50 g or 500 g, aerosol 1% by 50 ml, ointment for external use 1% by 50 g
Visasmodia with other drugs
It is possible to inactivate enzyme preparations to cleanse the wounds with their simultaneous use. Cimetidine Increases Leukopenia Risk.
Application measures
Information for the doctor: In the presence of hypersensitivity to sulfonamides, caution is advised to be able to develop AR (allergic reactions) in patients with congenital deficiency of glucose-6-phosphate dehydrogenase, impaired liver and kidney function. With long-term treatment of large area burns, control the blood formula (the development of leukopenia, thrombocytopenia or eosinophilia is possible). Monitor serum sulfadiazine concentrations, liver and kidney function, and the possible presence of sulfadiazine Burnazin urine. Superinfection https://zentherapycenter.com/let-r/roglin.php develop as a Burnazin of treatment.
Information for the patient: Avoid contact with eyes. Possible increase in body temperature due to unwanted side effects.
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Pharmachologic effect:
- Sulfanilamide preparation for topical use. It has a wide spectrum of antibacterial action, which includes almost all microorganisms that can infect burn wounds: Escherichia coli, Proteus spp., Staphylococcus spp., Klebsiella spp .; some types of mushrooms and yeast are also sensitive. Reduces the activity of SH-containing microbial cell enzymes. When applied to damaged skin, it dissociates with the release of silver and sulfanilamide ions, concentrations of which are sufficient to inhibit the growth of pathogens and at the same time do not have a damaging effect on tissue cells. Penetrates into Burnazin tissue. Slightly evaporates from the surface of the wound, has no unpleasant odor and is easily washed off with water.
Indications:
- Infected superficial wounds and burns with weak exudation, pressure sores, trophic and non-healing ulcers (including stump wounds), abrasions, skin grafts.
Contraindications:
- Hypersensitivity, suppression of bone marrow hematopoiesis, glucose-6-phosphate dehydrogenase deficiency, renal / hepatic insufficiency, porphyria, pregnancy, neonatal period and chest age (up to 1 month), deep purulent wounds and burns with severe exudation.
Side effects:
- Burning, itching, brownish-gray staining of the skin, skin allergic reactions (skin rash, photosensitivity); with prolonged use on large wound surfaces - systemic side effects (leukopenia, headache, dyspepsia).
Special instructions:
- In check treatment of patients with hepatic and / or renal failure, it is necessary to regularly monitor the concentration of sulfonamides in the plasma. Silver salts, reacting with atmospheric oxygen, metals, and other chemical components, especially when catalyzing thermal exposure, darken, so the drug should be stored in a closed container and away from heat sources. It is recommended that parts of the body treated with the drug be protected from direct sunlight.
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