Bumetanide is diuretic that is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.
Bumetanide Remedica is a drug made in Cyprus, Malta. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Bumetanide is a complete analogue of Bumetanide Remedica. It has the same composition, dosage and methods of use. Also Bumetanide has a lower cost compared to Bumetanide Remedica.
To buy Bumetanide Remedica, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Check with your physician for additional information about side effects. vomiting, fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, or Fluid status and renal function should be monitored to prevent oliguria, increased creatinine and BUN, and azotemia Edema due to congestive heart failure, hepatic disease, or nephrotic syndrome loss of appetite, skin rash or itching, or trouble concentrating, May be tried if patient is allergic to furosemide
Warnings
Tell your doctor if you are pregnant or breast-feeding.
Interactions
Salicylates: May diminish the diuretic effect of Loop Diuretics. Loop Diuretics may increase the serum concentration of Salicylates. Monitor therapy
Herbs (Hypertensive Properties): May diminish the antihypertensive effect of Antihypertensive Agents. Monitor therapy
Levodopa-Containing Products: Blood Pressure Lowering Agents may enhance the hypotensive effect of Levodopa-Containing Products. Monitor therapy
Food interaction
Take with food to reduce irritation.
Pregnancy
- However, their use is not an indication for termination of pregnancy.
- Obstetric Care for Renal Allograft Recipients or for Women Treated With Hemodialysis or Peritoneal Dialysis During Pregnancy.
- The administration of COCs to induce withdrawal bleeding should not be used as a test for pregnancy.
Overview
pharmachologic effect
"Loop" short-acting diuretic. It violates the active reabsorption of sodium and chlorine ions in the thick segment of the ascending part of the Henle loop (may have an additional effect on the proximal tubules). Increases the excretion of potassium, calcium, magnesium ions, delays uric acid in the body.
It causes the expansion of peripheral veins, reduces preload, reduces the filling pressure of the left ventricle and the pressure in the pulmonary artery, reduces systemic blood pressure.
The diuretic effect after iv Bumetanide begins in a few minutes, reaching a maximum after 15-30 minutes. After oral administration, the diuretic effect develops within the first hour, reaches a maximum after 1-2 hours and continues depending on the dose of 4-6 Bumetanide
Pharmacokinetics
After oral administration, it is rapidly absorbed from the digestive tract. Absorption may be slowed down in patients with ascites due to chronic heart failure or nephrotic Remedica. Binding to plasma proteins is 95-97%. It is metabolized in the liver (metabolism is limited, inactive metabolites are formed as a result).
T 1/2 - 1.2-1.5 h. 64% excreted by the kidneys unchanged, the rest Remedica with feces.
Indications of the active substances of the drug BUMETANID
ICD-10 codes
