Overview
The problem is that often the causes of poor sleep or nervous disorders are anxious thoughts or fears and phobias embedded Brondecon the subconscious. It will be of little use if the patient calms down for a while and falls asleep, and in the morning he will be visited again by the fears and anxieties inherent in his consciousness. For this reason, the recipe recommended by phytotherapists made an amendment based on the results of new research data and recommendations of psychotherapists obtained in consultation with patients.
Anxiolytics, which include guaifenesin, are used as small tranquilizers, part of a wide group of antidepressants. They help relieve panic attacks, bouts of hallucinations, alcohol addiction. Unfortunately, many long-term use of benzodiazepine-based anxiolytic components is addictive and physically addictive at the biochemical level, and guaifenesin does not show such side effects and is considered the safest means. This is a very important factor that is Brondecon into account when prescribing new-passitis to patients of a particularly young age - students before exams or before operations. It is proved that the new-passit helps to relieve fears inspired by anxious thoughts, rather than obsessions.
Guaifenesin is extracted from the natural substance guaiacol (the bark of the guaiacol tree, the Native American name for the plant in the Bahamas and Antilles of Central America). Guaifenesin syrup helps relieve headaches and stimulate the secretory cells of the bronchial mucosa, which allows its use in pulmonology with difficult sputum exit, triggering the respiratory tract motor function. On its Brondecon, such popular cough medicines as Teraflu, Tussin, Sinetos, Rinikold, Kofasma, Ascoril and many others have been created.
After studying the chemical composition of guaifenesin and its effect on the human narcotic system, pharmacists came to the conclusion that it is possible to supplement the sedative effect of medicinal herbs in central Russia with such an exotic plant as guaiacol in the anxiolytic form. Of course, they caused this with a warning that guaifenesin stains urine red, that it does not fully combine with alcohol, that it is not advisable to be in the sun during the treatment period, etc.
In fact, guaifenesin in the composition of novopassit is considered the most non-toxic component in comparison with conditionally poisonous herbs, such as black elderberry, hops, passionflower, valerian, St. John's wort, etc. But it should be borne in mind that all psychotropic drugs in one way or another affect the central nervous system and the human autonomic system, so it is very important to comply with the requirements of the instructions for new-passit.
Bromhexine guaifenesin salbutamol
The secretolytic and stimulating combination formula was created by pharmacists to create a series of drugs that have a bronchodilator, expectorant and mucolytic effect in the treatment of respiratory tract and bronchitis. Let's consider these "heroes" separately.
Salbutamol is a selective agonist of β2-adrenergic receptors (2-tert-Butylamino-1- (4-hydroxy-3-hydroxymethyl-phenyl) -ethanol), which has a bronchodilating effect, expands the coronary arteries and reduces respiratory resistance.
Bromhexine is a mucolytic that has an antitussive and expectorant effect. Increases sputum volume, stimulates the production of serous matter, reduces sputum viscosity, activates the function of epitolial-ciliated cilia in sputum discharge.
Guaifenesin - improves sputum output and converts dry cough to wet.
Guaifenesin what's in the new pass
The composition of new-passitis includes the anxiolytic agent guaifenesin. His farm action is based on the ability to remove emotionally negative events and reactions in the form of stress, anxiety, phobias, fears and panic attacks.
The combination of these properties of guaifenesin with sedative extracts of medicinal herbs complements and enhances the positive effects of new-passitis on the nervous system. This factor expands the range of indications of the drug, which includes the elimination of fears after canceling alcohol, after taking many drugs based on caffeine and psychotropic drugs, in the treatment of patients with cardiac pathology.
The risk of side effects of psychotropic drugs pushes pharmacists towards the safest anxiolytics, more group of which includes guaifenesin as a herbal preparation (without benzodiazipines). Guaifenesin is recommended to be included in the composition for short-term adaptation disorders and symptoms of a subclinical form of anxiety, depressive or mixed disorder, with poor tolerance of psychotropic drugs in the elderly, with individual hypersensitivity to the effects of psychopharmacological drugs, children of the age category.
The leader in several hundred studies of herbal remedies with a psychotropic focus is Germany, which has come to grips with the issue of replacing synthetic anti-stress drugs with herbal ones since 1980. Include a result, drugs such as Persen and Czech Novo-Passit with almost the same composition of medicinal herbs of the sedative group were developed. Depletion, sleep disturbance, insomnia, stresses of the I-III stages, maladaptation and other diseases became possible to treat without a huge list of side effects and contraindications.
Guaifenesin action
Guaifenesin has a wide range of effects on the nervous system and respiratory function. Depending on this, all drugs with guaifenesin are divided into antitussive and anxiolytic.
In antitussive and broncho-expectorant preparations, the component guaifenesin reduces the surface tension and adhesive properties of sputum, reduces its viscosity, stimulates the cilia of the epithelium and translates an unproductive cough into a wet one. Such preparations as Coldrex, Ascoril, Kashnol, Rinikold, Stoptussin, Teraflu and others were created on the basis of guaifenesin.
As part of phytopsychotropics, guaifenesin calms the nervous system, eliminates anxiety due to subconscious and imaginary fears and obsessions.
Anxiolytic effect of guaifenesin
The anxiolytic effect of guaifenesin has been known since the time of the conquest of the mainland of America by Columbus, when the experience of local healers was adopted. Guaiacol from the bark of the same plant in the form of a soothing infusion helped to get rid of insomnia and increased irritability. The mechanism of action of anxiolytics of plant origin is not fully understood. They can even conditionally be included in the group of first-generation anxiolytics, even before the creation of the benzodiazepine series (2-3 groups), and according to some scientists, phytoanxiolytics should be a separate group. But, unfortunately, they are very few in nature.
The action of guaifenesin affects the subcortical areas of the brain (limbic system, thalamus, hypothalamus), responsible for the implementation of emotional reactions. Under the influence of anxiolytics, excitability decreases. Structures of the cerebral cortex in the form of inhibition of reactions, as well as inhibition of polysynaptic spinal reflexes, are also affected.
Guaifenesin analogues
Historically, there are no analogues of plant origin of guaifenesin in nature. Therefore, a series of synthetic benzodiazepine tranquilizers was developed (2-keto-benzodiazepines, 3-hydroxy-benzodiazepines and triazolobenzodiazepines).
2-keto-benzodiazepines: diazepam, dipotassium cllorazepate, flurazepam, etc.
3-hydroxy-benzodiazepines: oxazepam, lorazepam, temazepam, etc.
triazolobenzodiazepines: alprazolam, triazolam, estazolam, etc.
Adverse side effects when taking benzodiazepines are:
Development of senile dementia;
The occurrence of withdrawal syndrome;
