Overview
Improves bile secretion, restores exocrine pancreatic function and endocrine - thyroid.
Regulates immunological reactions (activates Hot synthesis of antibodies, complement component C3, interferon), promotes phagocytosis, increases the body's resistance to infections.
It inhibits the release and accelerates the degradation of histamine, inhibits the formation of Pg Hot other mediators of inflammation and allergic reactions.
In low doses (150-250 mg / day by mouth) improves the complexing function of deferoxamine in chronic intoxication with Fe preparations, which leads to increased excretion of the latter.
Side effects
From the side of the central nervous Flu with rapid on / in the introduction - dizziness, feeling tired.
From the digestive system: when taken orally, irritation of the gastrointestinal mucosa.
Allergic reactions: skin rash, flushing of the skin.
Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.
Intensive consumption of chewable tablets Cold resorption of oral forms can cause tooth enamel damage. Symptoms: with prolonged use of large doses (more than 1 g) - headache, increased CNS excitability, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, gastrointestinal mucosa ulceration, inhibition of the function of the pancreatic insular apparatus (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular relief of the kidneys, moderate pollakiuria (when taking a dose of more than 600 mg / day).
Decreased capillary permeability (possibly worsening tissue trophism, increased blood pressure, hypercoagulation, the development of microangiopathies.
With the on / in the introduction of high doses - the threat of abortion (due to estrogenemia), erythrocyte hemolysis.
special instructions
Foods rich in ascorbic acid: citrus fruits, herbs, vegetables (peppers, broccoli, cabbage, tomatoes, potatoes). When storing foods (including prolonged freezing, drying, salting, pickling), cooking (especially in copper utensils), chopping vegetables and fruits in salads, preparing mashed potatoes, partial destruction of ascorbic acid occurs (up to 30-50% during thermal processing).
In connection with the stimulating effect of ascorbic acid on the synthesis of boot hormones, it is necessary to monitor renal function and blood pressure.
With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, during treatment, it must be regularly monitored.
In patients with a high iron content in the body, ascorbic acid should be used in minimal doses.
The effectiveness of the use of ascorbic acid for the prevention of diseases of the CVD and some types of malignant tumors is currently considered unproven.
Ascorbic acid is not recommended for pyorrhea, infectious diseases of the gums, hemorrhagic boots, hematuria, retinal hemorrhage, immune system disorders, depression, not associated with vitamin C deficiency.
The drug is considered insufficiently effective in the treatment of anemia, acne vulgaris, bronchial asthma, relief, atherosclerosis, peptic health, tuberculosis, schizophrenia, dysentery, collagenoses, skin ulcers, hay fever, fractures, drug intoxication, general hypothermia, to prevent thrombosis.
The administration of ascorbic acid to patients with rapidly proliferating and intensively metastatic tumors can aggravate the course of the process.
As a reducing agent, ascorbic acid can distort the results of cold laboratory tests (blood glucose, bilirubin, activity of “liver” transaminases and LDH).
The minimum daily Flu for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the "withdrawal" syndrome may develop in the newborn.
