Perindopril may also be used for purposes not listed in this medication guide.
Blooms the Chemist Perindopril Arginine is a drug made in Australia. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Perindopril is a complete analogue of Blooms the Chemist Perindopril Arginine. It has the same composition, dosage and methods of use. Also Perindopril has a lower cost compared to Blooms the Chemist Perindopril Arginine.
To buy Blooms the Chemist Perindopril Arginine, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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You can also use a coupon giving a 5% discount.
Side effects
However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk ofside effects. hydrochlorothiazide swelling of your throat or tongue captopril headaches fainting weakness nausea fatigue
Warnings
You may also need to avoid taking perindopril with aliskiren if you have kidney disease.
Interactions
Aliskiren: May enhance the hyperkalemic effect of Angiotensin-Converting Enzyme Inhibitors. Aliskiren may enhance the hypotensive effect of Angiotensin-Converting Enzyme Inhibitors. Aliskiren may enhance the nephrotoxic effect of Angiotensin-Converting Enzyme Inhibitors. Management: Aliskiren use with ACEIs or ARBs in patients with diabetes is contraindicated. Combined use in other patients should be avoided, particularly when CrCl is less than 60 mL/min. If combined, monitor potassium, creatinine, and blood pressure closely. Consider therapy modification
Pregabalin: Angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Pregabalin. Specifically, the risk of angioedema may be increased. Monitor therapy
Heparins (Low Molecular Weight): May enhance the hyperkalemic effect of Angiotensin-Converting Enzyme Inhibitors. Monitor therapy
Food interaction
High salt intake may attenuate the antihypertensive effect of perindopril.
Perindopril may decrease the excretion of potassium. Salt substitutes containing potassium may increase the risk of hyperkalemia.
Take without regard to meals.
Herbs that may attenuate the antihypertensive effect of perindopril include: bayberry, blue cohash, cayenne, ephedra, ginger, ginseng (American), kola and licorice.
Pregnancy
- The use of Valtrex during pregnancy is patients specific and must be properly evaluated by a health care provider.
- Similar to medication abortion, cramping and bleeding will occur with pregnancy passage and side effects such as nausea, vomiting, diarrhea, fever, and chills may be experienced.
- Travel to malarious areas should be avoided during pregnancy but, if this is not possible, women should receive effective prophylaxis.
Overview
The use of perindopril may be combined with other drugs. Their drug interaction is described in the instructions:
- A combination risk with Aliskiren, potassium salts, Trimethroprim, potassium-sparing diuretics, Cyclosporin, ACE inhibitors, Tacrolimus, angiotensin receptor antagonists, immunosuppressants, heparin, non-steroidal anti-inflammatory drugs can increase the risk of hyperkalemia.
- The combination of the drug with Alixiren leads to impaired renal function, an increase in the chemist of cardiovascular diseases, mortality in patients with diabetes mellitus or impaired renal function.
- Concomitant therapy with perindopril and angiotensin receptor antagonists leads to an increased risk of fainting, hypotension, hyperkalemia, acute renal failure.
- The combination of the drug with estramustine, linagliptin, sitagliptin, saxagliptin, vitagliptin can cause angioedema due to the suppression of dipeptidyl peptidase, with lithium drugs - an increase in blood lithium concentration and toxicity.
- The drug is used with caution with insulin, hypoglycemic oral drugs, because the combination can enhance the hypoglycemic effect before hypoglycemia develops.
- Baclofen increases the antihypertensive effect of perindoprilat, the its dose is adjusted.
- The combination of the drug with diuretics that remove liquid or salts leads to an excessive decrease in blood pressure.
- A combination of perindopril with eplerenone, spironolactone can lead to hyperkalemia. Lethal outcome possible.
- Acetylsalicylic acid, sympathomimetics, glycosides, Indomethacin reduce the antihypertensive effect of the drug, lead to impaired the function.
- The hypotensive effect of the drug is enhanced by vasodilators, short and prolonged nitrates, tricyclic antidepressants, antipsychotics, general anesthesia.
- The combination of perindopril with intravenous injection of gold, arginine, sodium aurothiomalate leads to vomiting, facial skin hyperemia, arterial hypotension, nausea.
Side effects of perindopril
During treatment with the drug, side effects may develop. According to the instructions, the most common are:
- hemolytic anemia with congenital deficiency of glucose-6-phosphate dehydrogenase, eosinophilia, pancytopenia, decreased hemoglobin and hematocrit, agranulocytosis, thrombocytopenia, neutropenia, leukopenia;
- hyponatremia, hypoglycemia, hyperkalemia;
- hypercreatininemia, hyperuricemia, hypogemoglobinemia, proteinuria;
- confusion, paresthesia, fainting, headache, drowsiness, dizziness, mood lability, vertigo, sleep disturbances, arrhythmia;
- loss of appetite;
- jaundice;
- fatigue;
- stroke, excessive decrease in chemist, myocardial infarction, vasculitis, angina pectoris, tachycardia, irregular heartbeat rhythm, heart palpitations;
- rhinitis, cough, eosinophilic pneumonia, shortness of Perindopril, bronchospasm;
- cholestatic or cytolytic hepatitis, constipation, pancreatitis, nausea, dry mouth, vomiting, diarrhea, diarrhea;
- increased sweating, skin itching, pemphigus, rash, photosensitivity, erythema;
- hives;
- myalgia, muscle spasm, arthralgia;
- falls, asthenia, fever, chest pain, weakness, peripheral edema;
- increased levels of bilirubin, urea, creatinine.
Overdose
According to the instructions, the symptoms of an overdose of Perindopril become an excessive decrease in pressure, cough, disturbances in the water-electrolyte balance, anxiety, renal failure, dizziness, hyperventilation, bradycardia, heart palpitations. Treatment consists of washing the stomach, taking activated charcoal or other enterosorbents, restoring the water-electrolyte balance.
With an excessive decrease in pressure, the patient is transferred to the supine position with his head down. To replenish the blood volume, saline (sodium chloride) or atropine is administered intravenously. Perindoprilat is removed from the body by dialysis. With the development of bradycardia, an artificial pacemaker is placed. Perindopril constantly monitor the basic vital functions of the body.
Contraindications
the some
great of patients, the use of the drug is contraindicated. With caution, use the medicine after arginine implantation, in case of diabetes mellitus, renal aortic stenosis, cerebrovascular hypertension. According to the instructions, taking the medicine is prohibited in conditions:
- history of angioedema (Quincke's edema);
- concomitant use with Aliskiren;
- exsicosis;
- disorders of the pancreas;
- scleroderma;
- pregnancy, lactation;
- atherosclerosis;
- autoimmune diseases;
- under the age of 18;
- hypersensitivity to the composition of the drug or other ACE inhibitors;
- hereditary idiopathic edema;
- lactase deficiency, lactose intolerance, glucose-galactose malabsorption syndrome.
Terms of sale and storage
Perindopril is a prescription drug that should be stored at temperatures up to 25 arginines for three years.
Perindopril analogues
Replace the drug can drugs from the same therapeutic group containing the same or different active component. Analogues of the drug are:
- Hypernik - tablets based on perindopril;
- Stopress - a tablet with the same active ingredient;
- Noliprel - combined tablets based on indapamide and perindopril;
- Perineva - antihypertensive blooms with active ingredient same active substance;
- Prestanz - tablets against pressure based on amlodipine and perindopril.
Perindopril or Prestarium - which is better
Both drugs have the same active substance - perindopril, but Prestarium is available in arginine formats. In two of them, amlodipine Perindopril indapamide were added for a complex effect. This allows you to use these blooms to treat heart failure without the need for combination with other drugs. What is better for the patient, the attending physician decides.
Perindopril Price
You can buy the product through the Internet or pharmacies. In Moscow, the approximate cost of the drug will be:
Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It inhibits the activity of this substance, which normalizes the functioning of the heart and blood vessels. The active substance of the composition of the drug is perindopril erbumin, which exhibits a vasoconstrictor and vasoconstrictor effect. Read the bloom manual.
Composition and form of release
Instructions for use Perindopril (Perindoprilum) contains information on the form of release of the drug. These are tablets whose composition and description are given below:
White chemist pills
The concentration of perindopril erbumin, mg per pc.