Bisoprolol may also be used for purposes not listed in this medication guide.
Bisoprolol Unicorn is a drug made in South Africa. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Bisoprolol is a complete analogue of Bisoprolol Unicorn. It has the same composition, dosage and methods of use. Also Bisoprolol has a lower cost compared to Bisoprolol Unicorn.
To buy Bisoprolol Unicorn, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
The incidence of adverse reactions is derived from treatment-related events as identified by the study investigators. Vomiting sulindac Sweating quinidine nifedipine procainamide slower heart rate swelling of your face, lips, or tongue
Warnings
It is not known whether bisoprolol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not use bisoprolol if you you are allergic to it, or if you have a serious heart condition such as:
- "AV block";
- severe heart failure; or
- slow heartbeats that have caused you to faint.
Interactions
Amiodarone: May enhance the bradycardic effect of Beta-Blockers. Possibly to the point of cardiac arrest. Amiodarone may increase the serum concentration of Beta-Blockers. Monitor therapy
Bretylium: May enhance the bradycardic effect of Bradycardia-Causing Agents. Bretylium may also enhance atrioventricular (AV) blockade in patients receiving AV blocking agents. Monitor therapy
Propafenone: May increase the serum concentration of Beta-Blockers. Propafenone possesses some independent beta blocking activity. Monitor therapy
Food interaction
Take without regard to meals.
Pregnancy
- If your period is more than a week late, you may be pregnant.
- Talk to your healthcare provider about the best way to feed your baby while taking Celexa.
Overview
I suffer from hypertension. With increased loads, on the weather, in stressful situations, there is often increased pressure. Autumn and spring exacerbation of the disease. Dizziness, unicorn, pain in the temples, in general, all the symptoms of hypertension come to me in full glory. I tried a bunch of everything, bisoprolol really helps. At the same time, the cost of the drug is much lower than present similar tablets in medicated. Therefore, at first I did not believe it and was skeptical of bisoprolol, but in vain. It helps well, and acts quickly - within half an hour symptoms disappear and pressure returns to normal. At least that's how it affects me.
To reduce blood pressure and as part of a comprehensive treatment of diseases of the cardiovascular system, doctors prescribe Bisoprolol (Bisoprolol) with a pronounced antihypertensive, anti-ischemic effect. Self-medication is contraindicated.
Composition and form of release
Bisoprolol is produced in the form of round, densely-coated biconvex tablets, beige. The medicine is packaged in blister packs of 10 pcs. or polymer bottles of dark glass of 30 pcs. In 1 cardboard pack can be 2, 3 or 5 blisters, instructions for use. The active substance is bisoprolol fumarate, 5 or 10 mg per 1 tablet. Chemical composition:
The composition of the film shell
iron oxide dye
The mechanism of action of bisoprolol
It is a selective β1-blocker that does not have an internal membrane-stabilizing, sympathomimetic activity.
Other pharmacological properties of bisoprolol:
- reduces myocardial oxygen demand;
- reduces cardiac output;
- reduces the excitability and conduction of the heart muscle;
- inhibits the synthesis of catecholamine and the formation of cyclic adenosine monophosphate from adenosine triphosphate;
- normalizes blood plasma renin activity;
- reduces the flow of calcium ions at the cellular level;
- inhibits atrioventricular (AB) conduction.
The medicine Bisoprolol is 80–90% absorbed from the digestive tract regardless of food intake. The maximum concentration in plasma reaches 1.5–2 hours after the use of a single dose. Binding to plasma proteins is 30%, the half-life is 10-12 Bisoprolol. Metabolism occurs in the liver with the formation of inactive metabolites. 98% of the drug is excreted unchanged by the kidneys (with urine), 2% - through the intestines (with bile).
Indications Bisoprolol
A drug reduces blood pressure in chronic hypertension. Appropriate pharmaceutical administration of bisoprolol in:
- heart ischemia;
- stable angina pectoris;
- chronic heart failure;
- atherosclerosis (as part of complex therapy).
Dosage and administration
Bisoprolol tablets are recommended to be taken in the morning on an empty stomach. A single dose must be swallowed whole, you can not pre-chew and dissolve, drink plenty of fluids. The course of treatment begins with a single dose of 0.005 g per day. With a slight excess of blood pressure, the indicated dosage is halved. The maximum daily dose is 0.02 g (for patients with renal dysfunction this medication 0.01 g per day). The scheme and course of treatment are selected individually.
special instructions
The drug Bisoprolol needs to be canceled gradually, otherwise a "withdrawal symptom" develops, which is accompanied by an attack of hypertension, tachycardia, arrhythmia. Other Bisoprolol directions:
- At the very beginning of the course, it is required to monitor blood pressure indicators daily, in a week to carry out such diagnostics already 1 time per week.
- If the patient has problems in the respiratory system, an assessment of the patient’s external respiration function is required before the course.
- Regular wear of contact lenses requires daily use of drops to prevent dry eyes.
- The use of bisoprolol can remember that the symptoms of thyroid disease and relapse of diabetes.
- Alcohol intake during treatment with an antihypertensive drug is contraindicated, since this interaction inhibits the functions of the nervous system.
- Since the drug reduces the rate of psychomotor reactions, it is not recommended to manage power mechanisms and engage in types of work that require an increased concentration of attention during treatment.
- With psoriasis or a predisposition to this disease, bisoprolol is prescribed with extreme caution.
Bisoprolol during pregnancy
The drug is contraindicated for use during gestation and breastfeeding. In exceptional cases, bisoprolol is prescribed during pregnancy, but canceled 72 hours before the expected date of onset of labor. Otherwise, a newborn baby develops hypoglycemia, arterial hypotension, bradycardia, and breathing is disturbed.
Drug interaction
Before starting drug therapy, you need to study the information on drug interactions, described in detail in the instructions:
- In combination with slow calcium channel blockers (Verapamil), myocardial contractility decreases, so this combination is contraindicated.
- Moxonidine, Rilmenidine and unicorn centrally acting antihypertensive agents reduce cardiac output.
- When used with antiarrhythmic agents of class 3, AV patency is impaired.
- With the combination of Bisoprolol and Isoprenaline, Dobutamine, other adrenergic agonists, the therapeutic effect of the last medications is reduced.
- Radiopaque iodine-containing diagnostic agents for intravenous administration increase the risk of anaphylactic shock.
- Bisoprolol is not recommended to be combined with MAO inhibitors, calcium antagonists, Flactaphenin, Sultoprid.
Side effects of bisoprolol
The drug is well tolerated by the body. In individual clinical cases, side effects may occur in which doctors adjust the dose, or completely cancel the drug:
