Overview
- Indications for use
- Mode of application
- Side effects
- Contraindications
- Pregnancy
- Interaction with other drugs
- Overdose
- Structure
Pharmachologic effect:Pills
bisacodyl have a laxative effect, manifested with constipation. The mechanism of laxative action is due to increased secretion of mucus in the large intestine, acceleration and enhancement of its peristalsis. The action is carried out through direct stimulation of nerve endings in the mucous membrane of the large intestine. Laxative effect occurs within 6-8 hours after oral administration of the drug.
Bisacodyl - contact preparation, insignificant part
bisacodyl (up
Cervagem 5%) is absorbed from the intestine and, after conjugation Bisacon the liver, is included in the intestinal-hepatic blood circulation, partially excreted by the kidneys.
Indications for use
- acute constipation;
- intestinal atony after prolonged bed rest, changes in diet or the environment;
- hypotension and flaccid peristalsis of the colon (for example, in elderly patients);
- bowel movement before examination (x-ray, endoscopic), before and after surgery, with severe cardiovascular diseases, during childbirth;
Mode of application
Assign per os (through the mouth) and per rectum (into the rectum). Adults take 1-3 tablets per night or 1-2 suppositories (suppositories) rectally (into the rectum). If necessary, take an additional 1-3 tablets in the morning 30 minutes before breakfast.
The usual single dose for adults is 5-10 mg (1 to 2 tablets).
Doses for children are set depending on age.
Side effects
There are colicky pains in the intestine, with a high dosage - diarrhea. With prolonged use of high doses, diarrhea can occur with excessive loss of fluid and electrolytes, the development of muscle weakness, seizures, arterial hypotension.
Contraindications
Intestinal obstruction, strangulated hernia, acute inflammatory diseases of the abdominal cavity (appendicitis, diverticulitis), lack of potassium, peritonitis, gastrointestinal bleeding, uterine bleeding, cystitis, spastic constipation, acute proctitis, acute hemorrhoids, hypersensitivity to bisacodyl.
Pregnancy
When treating with bisacodyl tablets, sufficient water should be consumed.
Interaction with other drugs
additionally the simultaneous use of bisacodyl tablets and:
- drugs that reduce potassium (carbenoxolone, corticosteroids, diuretics containing thiacide), potassium loss may increase;
- drugs that delay intestinal emptying (opiates), antacids, containing aluminum, anticholinergic, psychotropic, cholestyramine,
bisacodyl action decreases;
- cardiac glycosides - there may be an increased sensitivity to them due to a possible lack of potassium;
Laxatives may reduce the absorption of other drugs.
Overdose
In case of an overdose, colicky pains in the lower abdomen and, sometimes, signs of dehydration, especially in elderly patients and in children, can be observed. If necessary, gastric lavage, adequate rehydration.
It is necessary to control serum potassium. Antispasmodics can give a Bisacon effect. Special attention should be paid to maintaining water-electrolyte balance in elderly patients and children.
Release form:
Dragees of 0.005 g in a package of 30 pieces; candles of 0.01 g in a package of 12 pieces, tablets of 6.12 or 24 pieces in a blister strip packaging, as well as 30, 50, 100 in a polymer container.
Storage conditions:
List B. Store at a temperature of 15-30 ° C in a dry, dark place. Expiration date 1 year.
Synonyms:
Acetophenolpicolin, Alaxa, Alsilax, Bicolax, Bisacolax, Bisalax, Biscolax, Brocalax, Contactolax, Contalax, Demolaxin, Ducolax, Dulcolax, Durolax, Eulaxan, Enteralax, Phenolax, Laxacol, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxaxal, Laxaxal, Laxaxal, Laxaxal, Laxaxal, Pax, Laxaxal, Laxaxal, Laxaxal, Laxaxal, Pax, Pax Prontolax, Pirilax, Rhythmil, Sedolax, Spirolax, Teralax, Videx
An ordinary person perceives all laxative drugs in the same way. And even studying the instructions does not always provide an opportunity to catch important points. Indeed, many medical terms are simply misleading. Meanwhile, the drugs vary in composition, on the onset of the therapeutic effect and many other criteria.
How does the Bisacodyl medication describe the instructions for use? Pills can bring the desired effect? Let's understand.
Description of the drug
What is the medicine "Bisacodyl"? Instructions for use of the tablet are positioned as a laxative with a strong effect. Used in case of constipation.
The mechanism of action of the drug is to enhance the secretion of the mucosa in the colon. This stimulates the increase and acceleration of peristalsis. The drug has an effect on the nerve ganglia of the intestinal mucosa.
How long does Bisacodyl work? The beneficial effect after using the drug is noticeable after 6 hours. If the drug was used at night, then the necessary effect occurs in 8-10 hours. In the case of rectal suppositories, the effect of the medication can be observed after 15-45 minutes.
