It is used to treat TB (tuberculosis).
Bio-Strep is a drug made in South Africa. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Streptomycin is a complete analogue of Bio-Strep. It has the same composition, dosage and methods of use. Also Streptomycin has a lower cost compared to Bio-Strep.
To buy Bio-Strep, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Severe adverse reactions reported in the study included loss of appetite, fast heartbeat, fever, muscle weakness, rash, Brucella, nausea, persistent diarrhea even after stopping this medication,
Warnings
Interactions
Mannitol (Systemic): May enhance the nephrotoxic effect of Aminoglycosides. Avoid combination
Vancomycin: May enhance the nephrotoxic effect of Aminoglycosides. Monitor therapy
Oxatomide: May enhance the ototoxic effect of Aminoglycosides. Monitor therapy
Food interaction
Pregnancy
- If you are pregnant, you should talk to your healthcare provider about whether you have metabolic acidosis.
- This medicine should not be used during pregnancy, particularly the second and third trimesters, as it may be harmful to the developing baby.
Overview
Overdose.
Symptoms neuromuscular blockade up to respiratory arrest, in infants - CNS depression (lethargy, stupor, coma, deep respiratory depression).
Bio-Strep calcium chloride iv, anticholinesterase agents (neostigmine methyl sulphate s / c), symptomatic therapy, if necessary - mechanical ventilation.
Pregnancy and lactation.
During pregnancy, use only for health reasons (adequate and strictly controlled studies in humans have not been conducted). The concentration of streptomycin in the blood of the fetus is usually less than 50% of that in the blood of the mother. Streptomycin caused deafness in children whose mothers received it during pregnancy. It penetrates the placenta, is determined in the fetal blood serum at a concentration of about 50% of the concentration in the mother's blood serum. Has a nephro- and ototoxic effect on the fetus.
FDA Fetal Action Category - D.
In small amounts it Bio-Strep excreted in breast milk, it may affect the intestinal microflora, however, due to low absorption from the gastrointestinal tract, other complications in infants have not been recorded. Breast-feeding should be discontinued during treatment.
Precautionary measures.
Due to the high toxicity and possible development of resistance of microorganisms, the use of other infections (except tuberculosis) should be strictly limited. Previously treated tuberculosis patients should Bio-Strep prescribed streptomycin after laboratory determination of the sensitivity of mycobacteria secreted by the patient. In elderly patients, the daily dose should be present. For newborns and infants, streptomycin is prescribed only for health reasons. Treatment should be carried out under close medical supervision. In the presence of risk factors for the development of toxic effects, peak and residual concentrations of streptomycin in serum should be regularly determined (conduct therapeutic drug monitoring). Before and during treatment, the functions of the VIII pair of cranial nerves (audiogram, caloric tests) and kidneys should be regularly monitored. At the first signs of oto- or nephrotoxicity, the drug is canceled. People who have been in contact with streptomycin for a long time (medical personnel, pharmacists, pharmaceutical workers) may develop contact dermatitis. To avoid this, the necessary precautions should be observed (work with gloves, etc.)
Doses are Bio-Strep in mass (weight) terms or in units of action (ED); 1 unit is equal to 1 μg of chemically pure streptomycin base. Given the poor distribution of aminoglycosides in adipose tissue, in patients whose body weight exceeds the ideal by more than 25%, the daily dose calculated for the actual body weight should be reduced by 25%. In malnourished patients, the dose is increased by 25%.
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Dosage form
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See what "Streptomycin" is in other dictionaries:
STREPTOMYCIN - Streptomycinum. Action and application. Broad-spectrum antibiotic. Depending on the another, it has a bacteriostatic or bactericidal effect on many gram-positive and gram-negative, acid-resistant and penicillin . Domestic veterinary preparations