Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Benzocaine is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.
BiCOZENE is a drug made in United States. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Benzocaine is a complete analogue of BiCOZENE. It has the same composition, dosage and methods of use. Also Benzocaine has a lower cost compared to BiCOZENE.
To buy BiCOZENE, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Get emergency medical help if you have even mild symptoms: severe burning, stinging, or sensitivity where the medicine is applied; fast heartbeats; skin tenderness or redness; or dizziness, severe burning, stinging, or sensitivity where the medicine is applied; itching, skin tenderness or fast heart rate, and
Warnings
An overdose of numbing medication can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This can happen if you apply more than the recommended dose.
Interactions
Food interaction
Pregnancy
- The safety of this medicine for use during pregnancy has not been established.
- It has been used by a large number of women during pregnancy without any apparent harmful effects.
- Consider the risks of untreated depression when discontinuing or changing treatment with antidepressant medication during pregnancy and postpartum.
Overview
The drug is taken under the supervision of a doctor, because the medicine has such side effects:
- Contact find (skin inflammation).
- Hypersensitivity reactions such as burning, tingling, and itching. In rare cases, swelling and urticaria occur.
- Temporary decrease in sensitivity.
- With a significant overdose, methemoglobinemia (a violation of the transfer of oxygen by blood cells from the lungs to tissues) may occur.
Overdose
Taking large doses of the drug can lead to side effects such as shortness of breath, cyanosis, dizziness, and in rare cases, methemoglobinemia. To eliminate these symptoms, symptomatic treatment is necessary. Methylene blue solution may also help.
Contraindications
The drug is contraindicated:
- There is hypersensitivity to benzocaine and to individual components of drugs containing benzocaine.
- Patients under two years of age are prohibited from using this medicine.
During pregnancy and breastfeeding, it is advisable to refuse the use of the drug, since there is little experimental data on the effect of this substance on the fetus of a child. However, benzocaine can be used if the number of positive therapeutic effects exceeds the number of negative side effects.
Interaction
Benzocaine interacts with other substances as follows:
- Visibly reduces the activity of sulfonamides (strong antimicrobials). Explanation - Benzocaine is one of the metabolites of PABA.
- Increased activity of acetylcholinesterase inhibitors may decrease benzocaine metabolism.
Benzocaine is sold in the following forms:
- Anestezin tablets containing 0.3 grams of active ingredient - 80 rubles will have to be paid per package (12 tablets).
- Dentisprey (benzocaine is a spray for application to the affected area of the skin) - for one bottle (5 milliliters) you will have to pay 90 rubles.
- Benzocaine in the form of an BiCOZENE (Relief Advance, Benzocaine ointment, Anestezin ointment and others) - you will have to pay 75 rubles for a tube (30 grams) (in the case of Relief Advance - 100 rubles).
Pharmacology and chemistry are two inseparable things. Many chemical experiments in various directions have led to the creation of new drugs. And the answer to the question: “Benzocaine - what is it?” Will be unequivocal: a chemical substance used in medicine.
Chemistry and medicine
In 1898, a major breakthrough occurred in medicine - substances were discovered that could reduce pain - anesthetics. To this day, anestezin and novocaine are used in clinical medicine as local anesthetics. Anestezin is a chemical substance benzocaine. Its correct scientific name is 4-aminobenzoic acid ethyl ester. To the question: “Benzocaine - what is it?”, One can easily answer - anesthetic.
Chemical compound properties
Benzocaine is synthesized as a white crystalline powder. It smells nothing, but if you try it, you can feel a slightly bitter taste, until your tongue is numb. Numbness, by the way, passes literally in 20 minutes.
This substance is highly soluble in ethanol, fatty oils, in ether and chloroform. But in order to dissolve 1 gram of benzocaine, you need 2.5 liters of water. Benzocaine is widely used in various fields of medicine - from local painkillers to lubricants.
Pharmacological properties of benzocaine
BiCOZENE sensation of pain is associated with irritation of certain cellular receptors. Calcium Ca 2+ ions, passing through the cell membrane, cause an impulse, which is then perceived as pain. One of the means that violate the penetration of ions into the cell is benzocaine. The use and action of this substance is based on its ability to block calcium channels, thereby creating an obstacle to the sensation of pain. This chemical substance is poorly absorbed, having only a local effect, and poor absorption does not depend on the method of use of drugs with benzocaine, and they are used as local surface agents and are taken orally. Since benzocaine-based drugs have only a local anesthetic effect, their effect is short in duration - 15-20 minutes.
How does the drug work?
Benzocaine is an anesthetic due to its ability to block the calcium channels of the cell membrane, through which there is irritation of certain cell receptors. Thus, transmission of a nerve impulse is excluded to define irritation as pain. Benzocaine is an active component of many drugs and intimate products. Such drugs are released in the form of ointments, gel, sprays. Therefore, one cannot say unequivocally - benzocaine, what is it? After all, this is a fairly large number of pharmacy products for various purposes.
Preparations with benzocaine are prescribed for use both locally and taken orally. The dosage and mode of use of this substance is determined by the attending physician. Preparations in the form of ointments, creams, liquids are applied to the surface of the skin with light rubbing movements. If it is necessary to anesthetize the ear canal, then 4-5 drops of the drug are instilled into the ear, then closed with a cotton or gauze swab. The analgesic effect is not too long, so the drug can be applied after 60-120 minutes. About analgesia in dental practice, benzocaine is applied to the gums in the form of a powder or ointment.
Medicines with benzocaine, which are taken orally, are prescribed by a doctor according to his chosen scheme. The maximum daily dose of benzocaine for an adult is 1.5 grams.
