Loperamide is used to treat diarrhea.
Betaperamide is a drug made in South Africa. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Loperamide is a complete analogue of Betaperamide. It has the same composition, dosage and methods of use. Also Loperamide has a lower cost compared to Betaperamide.
To buy Betaperamide, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Tell your doctor about any unusual or bothersome side effect. Vomiting Skin rash Itching Stomach pain, discomfort, or enlargement Difficulty breathing Dry mouth Drowsiness Wheezing
Warnings
You should not breast-feed while you are using loperamide.
Interactions
Ranolazine: May increase the serum concentration of P-glycoprotein/ABCB1 Substrates. Monitor therapy
Haloperidol: QT-prolonging Agents (Indeterminate Risk - Avoid) may enhance the QTc-prolonging effect of Haloperidol. Monitor therapy
QT-prolonging Agents (Highest Risk): QT-prolonging Agents (Indeterminate Risk - Avoid) may enhance the QTc-prolonging effect of QT-prolonging Agents (Highest Risk). Management: Monitor for QTc interval prolongation and ventricular arrhythmias when these agents are combined. Patients with additional risk factors for QTc prolongation may be at even higher risk. Monitor therapy
Food interaction
Take without regard to meals. Increase liquid intake.
Pregnancy
- Years of Birth Defects Surveillance at the Centers for Disease Control and Prevention.
- All triptans are considered Category C in pregnancy.
- If you are more than 12 hours late taking your pill, you will not be protected against pregnancy.
Overview
Loperamide - antidiarrheal agent. It reduces the tone and motility of the smooth muscles of the intestine, apparently due to binding to opioid receptors in the intestinal wall. Inhibits the release of acetylcholine Betaperamide prostaglandins, reducing peristalsis and increasing intestinal transit time.
Increases the tone of the anal sphincter. The action is fast and lasts 4-6 hours.
Pharmacokinetics
Absorption - 40%. Does not cross the blood-brain barrier. Almost completely metabolized in the liver by conjugation. It is excreted mainly by the intestines; a small part is excreted by the Betaperamide (in the form of conjugated metabolites).
Structure
Loperamide hydrochloride + excipients.
Indications
- symptomatic treatment of acute and chronic diarrhea of various origins (allergic, emotional, drug, radiation: with a change in diet and quality of food, in violation of metabolism and absorption: as an adjuvant for diarrhea of infectious origin);
- stool regulation in patients with ileostomy.
Release Forms
Instructions for use and dosage
Inside, without chewing, washing down with water.
Adults with acute and chronic diarrhea are initially prescribed 2 capsules (0.004 g), then 1 capsule (0.002 g) after each bowel movement in case of loose stool. In case of acute diarrhea, children over 6 years old are prescribed 1 capsule (0.002 g) after each bowel movement in case of loose stool.
The maximum daily dose. In acute and chronic diarrhea in adults - 8 capsules (0.016 other in children - 3 capsules (0.006 g).
After stool normalization or in the absence of stool for more than 12 hours, treatment with Loperamide should be discontinued.
Side effect
- allergic reactions (skin rash);
- drowsiness or insomnia;
- dizziness;
- dry oral mucosa;
- intestinal colic;
- pain or discomfort in the abdomen;
- nausea, vomiting;
- flatulence;
- urinary retention;
- intestinal obstruction.
Contraindications
- hypersensitivity to the drug;
- lactose intolerance;
- lactase deficiency or glucose-galactose malabsorption;
- diverticulosis;
- intestinal obstruction;
- ulcerative colitis in the acute stage;
- diarrhea on the background of acute pseudomembranous enterocolitis;
- in the form of monotherapy - dysentery and other infections of the gastrointestinal tract;
- pregnancy (1 trimester);
- lactation period;
- loperamide capsules are not prescribed for children only here 6 years.
Pregnancy and lactation
Contraindicated in 1 trimester of pregnancy.
In the 2nd and 3rd trimesters of pregnancy, Loperamide can be prescribed in cases where the expected benefit of therapy for the mother outweighs Veragel-DMS potential risk to the fetus.
Since a small amount of loperamide is found in breast milk, intake during breastfeeding is not recommended.
special instructions
In the absence of effect after 2 days of using Betaperamide, you must consult a doctor.
If constipation or bloating develops during treatment, loperamide should be discontinued. In patients with impaired liver function, careful monitoring of signs of toxic damage to the central nervous system is necessary.
During the treatment of diarrhea, it is necessary to replenish the loss of fluid and electrolytes.
During the treatment period, caution must be exercised when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Drug interaction
It is believed that with the simultaneous use of colestyramine may reduce the effectiveness of loperamide.