Bendamustine is used to treat chronic lymphocytic leukemia. Bendamustine is also used to treat indolent B-cell non-Hodgkin lymphoma after other medicines have been tried without successful treatment of this condition.
Bendamustine Hydrochloride Baxter is a drug made in New Zealand. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Bendamustine is a complete analogue of Bendamustine Hydrochloride Baxter. It has the same composition, dosage and methods of use. Also Bendamustine has a lower cost compared to Bendamustine Hydrochloride Baxter.
To buy Bendamustine Hydrochloride Baxter, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
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Side effects
Severe adverse reactions reported in the study included severe ongoing nausea, vomiting, or diarrhea; fever, chills, or itching during or shortly after the injection; nausea, vomiting, diarrhea, constipation; headache, tiredness; or fever, cough, mouth sores, trouble breathing; pain, swelling, redness, skin changes, or signs of infection where the medicine was injected;
Warnings
Using bendamustine may increase your risk of developing certain types of cancer. Ask your doctor about this risk.
You should not breastfeed while using bendamustine.
Tell your doctor if you have ever had:
- a weak immune system;
- fever or other signs of infection;
- tuberculosis;
- herpes zoster (also called shingles)
- a metabolic disorder or electrolyte imbalance;
- liver disease;
- kidney disease; or
- if you smoke.
Interactions
CloZAPine: Myelosuppressive Agents may enhance the adverse/toxic effect of CloZAPine. Specifically, the risk for neutropenia may be increased. Monitor therapy
CYP1A2 Inducers (Moderate): May decrease the serum concentration of Bendamustine. Concentrations of active metabolites may be increased. Monitor therapy
Palifermin: May enhance the adverse/toxic effect of Antineoplastic Agents. Specifically, the duration and severity of oral mucositis may be increased. Management: Do not administer palifermin within 24 hours before, during infusion of, or within 24 hours after administration of myelotoxic chemotherapy. Consider therapy modification
Food interaction
Pregnancy
- Pregnancies have been reported by users of combined hormonal contraceptives who also used some form of St.
- There are no adequate, controlled studies during human pregnancy.
- Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, and decrease your risk of ovarian cysts.
Overview
I experienced bendamustine on myself. He helped me a little. He had few side effects, although I was nauseous and had terrible fatigue. His toxicity is significantly less than that of many cytostatics, so the hair does not fall out. I think if my tumor was smaller then, and not in the lungs, but allow in the nodes, then the results would be better. But then I needed to urgently reduce the tumor in the lung, so there was no time to wait until bendamustine worked. I then reached the start of the SGN-35 test, and then you all know.
But. I also want to draw attention to the fact that bendamustine is now being tested for all tumors for which doxirubicin is used (red chemistry, brrrrr.). For example, here is a test for ovarian tumors
And immeasurably for all kinds of leukemia and lymphomas, including T-cell.
Which Bendamustine not mean that this is a new magic wand. But still an additional tool in the fight.
By the way, pay attention- since the medicine is already registered for a certain lymphoma (chronic lymphoblastic leukemia) in the USA, then it can already be used without the protocol. I got it exactly like that - i.e. without participation in CI (although CI goes to the Sloan-Kettering Memorial Hydrochloride New York). Incidentally, I did not completely abandon him - if necessary, I will return to him. Still, I think he eliminated two nodes from me - they burned on PET and were 1x2 cm in size before treatment, and after two courses (two days in a row, every four weeks) they no longer burned and were smaller.
Well, it seems that this is all that a cat knows about bendamustine. After some time I’ll Hydrochloride this post up to hang there for public viewing.
Indications for use
- Chronic lymphocytic leukemia (the effectiveness of the use in first-line therapy compared to other chemotherapy drugs except chlorambucil has not been established).
- Indolent non-Hodgkin lymphomas in monotherapy in patients who experienced progression on the background or within 6 months after completion of therapy with rituximab and in combination therapy as a first-line therapy.
- First-line therapy of multiple myeloma (stage II with progression or stage III according to Dury-Salmon) Bendamustine combination with prednisolone for patients older than 65 years of age who are not shown autologous stem cell transplantation and who have clinical manifestations of neuropathy at the time of diagnosis that prevent the use of therapy with the inclusion of thalidomide or bortezomib.
Possible analogues (substitutes)
Active substance, group
Dosage form
powder for the preparation of a concentrate for the preparation of a solution for infusion
Contraindications
- Hypersensitivity to the active substance or any of the auxiliary baxters of the Bendamustine, or their intolerance;
- The number of neutrophils is less than 1500 / μl and / or platelets less than 75000 / μl;
- Surgical procedures less than 30 days before the start of therapy;
- Infections, especially accompanied by leukocytopenia;
- Children's age (lack of data on efficacy and safety).
With caution, therapy is prescribed for mild liver failure, with Hydrochloride renal baxter. Patients with a history of serious cardiological diseases (myocardial infarction, episodes of ischemia, arrhythmia) need careful monitoring of the water-electrolyte balance, especially potassium, and ECG monitoring during treatment.