Overview
Daily dose Baclofen should be no more than 100 mg.
For patients with renal dysfunction, as well as during dialysis, the dose is reduced to 5 mg per day.
Side effects
When using the drug Baclofen side effects in most cases occur with a sharp increase in dose, or in the elderly. Most often, side effects subside and stop after a dose reduction. Treatment should be discontinued in case of severe side effects.
Side effects on the central nervous system: general weakness of the body (fatigue, dizziness, nausea, headache, drowsiness, insomnia at night, weakness). Mental disorders, such as agitation, depression, hallucination euphoria, disorientation, paresthesia, asthenia, are rarely observed. Other side effects include muscle pain, poor coordination, dry mouth, tremors, holding your breath, vomiting, nightly fears, and restless sleep. In patients with epilepsy, the threshold of medicine and attacks may decrease. In rare cases, the drug can cause hypotension, breathing problems, tachycardia, loss of consciousness, chest pain. Also, the drug can provoke problems with the digestive system: abdominal pain, anorexia, diarrhea, constipation, blood in the feces, impotence. A side effect is also the absence, incontinence or effectiveness of urine, significant discharge of blood with urine, impotence, impaired ejaculation. Violations of the sensory organs, hyperhidrosis, allergic skin reactions, ankle swelling, excessive sweating, exacerbation of spastic conditions may occur.
Contraindications
Contraindications to the use of the drug Baclofen are: hypersensitivity to the components of the drug, peptic ulcer.
Pregnancy
A drug Baclofen penetrates the placenta this medication the mother, and also excreted in milk. Taking the drug during pregnancy or breastfeeding is possible if, according to the doctor, the result is the ratio of benefit to the mother / potential risk to the fetus (child) is quite high.
Interaction with other drugs
Baclofen can increase the threshold of action of alcohol and drugs that affect the central nervous system, as a result - increased sedative effect;
Reception medical lithium salts - intensification of hyperkinetic symptoms of manifestations;
Antihypertensive drugs - increased hypotensive effect;
Drugs whose side effect is renal failure can cause intoxication of the body;
Carbidopa, levodopa - with Parkinson's disease, mental disorders are possible;
When interacting with the drug fentanyl - an increase in the period of anesthesia.
Overdose
In case of overdose Baclofen These side effects may occur. Such reactions are also possible: peripheral vasodilation, hyporeflexia or areflexia, anxiety, visual impairment, bradycardia, convulsions, decreased body temperature, increased levels of lactate dehydrogenase, ALT and AST.
At the first stages of an overdose, gastric lavage is recommended, as well as the use of laxative salts if necessary.
coma - intubation is performed before gastric lavage; respiratory disorders - artificial respiration and procedures are required to restore the stability of the cardiovascular system; cramps - intravenous diazepam.
There is no specific antidote to the active substance of the drug Baclofen.
In case of intoxication, a violation of the central nervous system (especially with inhibition of respiratory function and sleep loss, intravenous administration of 1 - 2 mg of physostigmine for 5 to choice minutes). In the absence of a positive effect, physostigmine must be reintroduced 30-60 minutes after the previous administration.
To increase the excretion of baclofen from the body, diuretics are used simultaneously with the intake of a large amount of liquid.
Storage conditions:
A drug Baclofen store in a dry place, here from direct rays, at t≤ 25 ° C. Keep away from children.
Beclotab form:
Baclofen - tablets in packs; in a polypropylene jar 50 pcs.; in a pack of cardboard 1 can.
Tension and muscle spasms often worsen the course of many pathologies of the musculoskeletal system. The patient experiences discomfort or severe pain. To eliminate such symptoms, drugs from the group of muscle relaxants are used. They allow Beclotab a short check to ease pain and ease the patient's condition. One of such agents is Baclofen, a muscle relaxant with a good therapeutic using
Composition and form of release
The pharmacological agent belongs to the central muscle relaxants and is available in the form of coated tablets. In the form of ointment and injections, it is not available. The active component in the composition of the drug is the substance baclofen, due to which the therapeutic effect is realized. Its dosage may be 10 or 25 mg. The drug also contains several auxiliary substances:
- potato starch;
- talc;
- lactose;
- ethyl cellulose;
- gelatin.
Biconvex tablets are painted white and packaged in 50 polyethylene bottles. Each of them is in a cardboard box, where you can also find instructions for use. The price of Baclofen tablets starts at 100 rubles and may vary depending on the region of distribution.
As a rule, you can buy the drug without a prescription, but in some areas it is required, which eliminates the possibility of self-medication.
Pharmacological Beclotab Pharmacological properties
As a central muscle relaxant, the medication performs its function well and, when ingested, quickly and effectively relaxes the skeletal muscles. The active component inhibits the action of intermediate neurons, helping to slow down the passage of a nerve impulse to muscle tissue.
This process significantly reduces stress in problem areas and facilitates the course of the underlying disease. Elimination of muscle spasm helps to ease pain and prevents complications. The drug has a positive effect on the mobility of articular joints, increases their amplitude and prevents stiffness, which is often observed with degenerative-dystrophic changes.
There is evidence that the drug has the ability to alleviate and prevent clonic convulsions, which often disturb patients with various neurological disorders.
With a course dose, the drug has the same positive effect on muscles and joints as massage or physiotherapy exercises. With the combination of these methods of therapy, it is possible to achieve complete recovery without the use of potent analgesics, non-steroidal anti-inflammatory and hormonal drugs.
The action of the drug is complemented by a medical anti-inflammatory effect. The medicine not only relieves the symptoms of inflammation, but also prevents the development and progression of the pathological process. In combination with other means, it helps to alleviate the course of the disease.
Absorption and assimilation
