Aspirin is a salicylate (sa-LIS-il-ate). It works by reducing substances in the body that cause pain, fever, and inflammation.
Bayer PM Aspirin Plus Sleep Aid is a drug made in United States. You need a doctor's prescription to buy it. But its analogues can be bought online anywhere in the world without going to a specialist.
Aspirin is a complete analogue of Bayer PM Aspirin Plus Sleep Aid. It has the same composition, dosage and methods of use. Also Aspirin has a lower cost compared to Bayer PM Aspirin Plus Sleep Aid.
To buy Bayer PM Aspirin Plus Sleep Aid, click on the "buy now" button and then in our online store select the medicine and the desired dosage. Follow the instructions below.
Free delivery is valid for purchases from $200. We deliver medicines around the world and provide the best prices.
You can also use a coupon giving a 5% discount.
Side effects
Tell your doctor right away if you develop signs of kidney problems such as a change in the amount of urine. drowsiness; or upset stomach, heartburn; severe nausea, vomiting, or stomach pain; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
Warnings
To make sure this medicine is safe for you, tell your doctor if you have:
- asthma or seasonal allergies;
- stomach ulcers;
- liver disease;
- kidney disease;
- a bleeding or blood clotting disorder;
- gout; or
- heart disease, high blood pressure, or congestive heart failure.
Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.
Aspirin can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Interactions
Salicylates: May enhance the anticoagulant effect of other Salicylates. Monitor therapy
Thrombolytic Agents: Salicylates may enhance the adverse/toxic effect of Thrombolytic Agents. An increased risk of bleeding may occur. Monitor therapy
Prostacyclin Analogues: May enhance the antiplatelet effect of Agents with Antiplatelet Properties. Monitor therapy
Food interaction
Take with a full glass of water.
Take with food to reduce gastric irritation.
Avoid alcohol, alcohol appears to cause a 50 to 100% increases in ASA serum levels.
Pregnancy
- The more consecutive tablets you have missed, the higher the risk that you might fall pregnant.
- Only a pregnancy test that checks for the presence of the hCG human chorionic gonadotropin pregnancy hormone will tell you if you are pregnant or not.
Overview
Application features
Children under 15 years of age should not be prescribed a drug containing acetylsalicylic acid, since in the case of a viral infection, the risk of Reye syndrome increases.
Acetylsalicylic acid can cause bronchospasm, an attack of bay asthma, or other Aid reactions. Risk factors are a history of asthma, fever, nasal polyps, chronic bronchopulmonary diseases, a history of allergies (allergic rhinitis, skin rashes).
Acetylsalicylic acid can increase bleeding tendency due to its inhibitory effect on aspirin aggregation. This should be considered when surgical interventions are necessary, including minor interventions such as tooth extraction. Before surgery, to reduce bleeding during surgery and in the postoperative period, you should stop taking the drug for 5-7 days and notify the doctor.
If it is necessary to use the drug during lactation, breastfeeding should be discontinued.
Acetylsalicylic acid reduces the excretion of uric acid from the body, which can cause an acute attack of aspirin in susceptible patients.
Varieties, names and forms of release of Aspirin
Currently, aspirin, as a rule, means all drugs containing as an active ingredient acetylsalicylic acid. However, the trade name "Aspirin" is carried by only a few sleeps of the drug manufactured by the German company Bayer. All other drugs containing acetylsalicylic acid have other official names, but in everyday speech they are all called “Aspirin”. That is, bay is a transfer of the common, long-known name of the original and patented drug to all its analogues in the active substance (synonyms and generics). Since the effects, rules of use and sleep of all Aspirin synonyms are bay the same, in the future text of the article we will describe the properties of the entire combination of acetylsalicylic acid preparations, the name "Aspirin" is used to indicate.
So, Aspirin is available in two dosage forms:
one. Tablets for oral administration;
2. Effervescent tablets for dissolution in water.
Effervescent tablets are produced under three commercial names - "Aspirin 1000", "Aspirin Express" and "Aspirin C", and are used to relieve pain. Aspirin effervescent tablets are currently available in two versions - containing only acetylsalicylic acid or acetylsalicylic acid + vitamin C. Accordingly, a drug with vitamin C is called "Aspirin C", and without it - simply "Aspirin 1000" and "Aspirin Express".
Tablets for oral administration are available in two varieties - for stopping pain, heat and for long-term use for the prevention of thrombosis. Pills for stopping pain and heat are called plus Aspirin, and pills for the prevention of thrombosis - "Aspirin Cardio".
Structure
Aspirin - recipe
A Latin recipe for Aspirin is written as follows:
Rp: Tab. “Aspirin” 500 mg
D.t.d.№ 20
S. Take by mouth one tablet 3 times a day.
In the recipe after the letters effectiveness the release form of the drug is indicated (in this case tablets - Tab.) and its name in quotation marks. After the name, Aid dosage is plus in mg or g. After the letters "D.t.d." indicates the number of tablets that the pharmacist must give to a person upon presentation of this prescription. After the letter "S", it is indicated how to take the drug.
Therapeutic effect
The action of Aspirin is due to the active substance that is part of the drug - acetylsalicylic acid. This substance is capable of exerting the following main effects:
- Analgesic effect;
- Antipyretic effect;
- Anti-inflammatory effect;
- Antiaggregant action.
The listed effects of acetylsalicylic plus are due to its ability to block the work of the enzyme
cyclooxygenasewhich provides the production of biologically active substances responsible for the development of a pain impulse, an inflammatory reaction and an increase in body temperature. By blocking the work of the enzyme, Aspirin stops the synthesis of substances that cause inflammation, temperature and pain, thereby eliminating these symptoms. Moreover, the drug eliminates the symptoms, regardless of in which organ or part of the body they are localized. Since Aspirin does not affect the central systems of pain perception, it is assigned to the sleep of non-narcotic painkillers.
At low dosages, Aspirin is able to reduce blood coagulability and the associated thrombosis, providing an antiplatelet effect. This effect is achieved by suppressing the production of thromboxane A2, a substance that causes platelets to stick together.
In principle, at higher dosages, Aspirin also has Aid antiplatelet effect, but in these cases, in addition make use it, the drug also has an analgesic, anti-inflammatory and antipyretic effect, which is side and unnecessary if it is only necessary to suppress thrombosis.
Therefore, to achieve an isolated antiplatelet effect, Aspirin must be taken in small doses, 100 to 300 mg per aspirin. And to lower the temperature, relieve pain and reduce the inflammatory process, Aspirin is taken in higher dosages, 300-1000 mg per day.
Indications for use