Overview
Means "Baclofen": instructions for use
The scheme and quantity is set individually to identify the minimum effective volume that does use that cause side effects. The medication "Baclofen" recommended for use with food. Before starting therapy, it is necessary to determine the maximum effectiveness of the drug. Increasing the dosage is carried out with caution. This is especially true for patients older than 65 years. Increasing the dose is carried out until the patient is stabilized. This is especially important for those who need movement to reduce weakness in Baclofen limbs or, if necessary, achieve a reduction in generic tension. In the absence of effectiveness for six weeks when taken in the recommended therapeutic amounts, it is necessary to decide on the extension of the course. Reception of means "Baklofen" the application instruction recommends to carry out according to a certain scheme. For different age categories, the course of therapy is.
Scheme for adults
- 1-3 days - 0.5 tab. (10 mg) 3 r / day.
- 4-6 d. - 1 tab. 3 r / day.
- 7-9 d. - 1.5 tab. 3 r / day.
- 10-12 d. - 2 tab. 3 r / day.
In most patients, the therapeutic effect is observed when taking 30-75 mg / day. If necessary, an increase in the amount of funds received is allowed. Those patients who need to drink the medicine in large generics are prescribed 25-mg Baclofen tablets. The instruction warns that the maximum amount is 100 mg / day. It should not be exceeded. The duration of admission will depend on the clinical presentation. It is not recommended to suddenly stop therapy. This is associated with a high risk of hallucinations and an exacerbation of the spastic state.
Recommendations for elderly patients
In general, the dosage for them is prescribed according to the scheme described above. Particular care should be taken when increasing the amount of funds at a time. In elderly patients, side effects are more likely to occur.
Reception scheme for children
Therapy should be started with a reduced dosage. The amount of the product is calculated in accordance with the weight of 0.3 mg / kg / day. The total dose is divided into 2, and preferably 4 doses per day. An increase in the amount of medication is carried out with an interval of a week until the desired state is reached. In general, it is recommended to use a maintenance dosage per day - 0.75-2 mg / kg. The maximum amount of the drug is 40 mg for patients under eight years of age. For patients with 8 years of age - 60 mg. Tablets are not recommended for children whose body weight is less than 33 kg.
Special categories Baclofen patients
Patients with impaired renal activity need a dose reduction of up to 5 mg / day. In the terminal stage of kidney failure, medication is prescribed only when the intended benefit outweighs the potential risk. For patients in contain condition, signs of early poisoning are https://zentherapycenter.com/let-l/loxalate.php (they include, for example, coma, drowsiness). Undesirable effects are often observed in patients with spastic conditions of cerebral origin. In this regard, he sets the appropriate dosage regimen. In addition, these patients should be continuously monitored by a physician.
Contraindications
Means "Baclofen" the instruction for use generics not recommend for hypersensitivity to any component. Contraindications include exacerbation of a duodenal ulcer and stomach. No medication prescribed for porphyria.
Side effect
Undesirable consequences may occur at the very beginning of therapy with Baclofen. Reviews of specialists about the drug, in general, are positive. Doctors note that side effects are eliminated when adjusting the regimen. Most often, complications occur in elderly patients. The negative consequences in the form of drowsiness and nausea are the body's reaction to a rapid increase in dose. As practice shows, complications are transient. In severe cases, drug withdrawal is required. If nausea persists after a dose reduction, it is recommended to drink the product with milk. The most serious consequences, according to doctors, are noted in mentally ill patients or undergoing cerebrovascular pathologies (stroke, for example). In some cases, a paradoxical reaction to the medication may be noted. It is manifested by an increase in spasticity. In some patients, the likelihood of respiratory depression is increased. In this regard, careful monitoring of the activity of the heart and respiratory organs is necessary. This is especially true for patients with concomitant pathologies.
Interaction with other means
While taking the medication "Baclofen" with other drugs that affect the central nervous system, alcohol, synthetic opiates, their sedative effect increases. In patients sharing lithium salts, hyperkinesia may increase. Tricyclic antidepressants enhance the activity of the drug "Baclofen" and significantly reduce muscle tone. With the simultaneous administration of antihypertensive drugs, their effect is potentiated. In some present, dosage adjustment may be required. Medicines that affect renal function, for example, Ibuprofen, reduce the https://zentherapycenter.com/let-p/pulmotil-200.php of excretion of the Baclofen drug. Special attention should be paid to patients with Parkinson's disease. With the simultaneous administration of Levodopa and Carbidopa with Baclofen, confusion is likely. Perhaps the development of mental arousal and hallucinations.
Means "Baclofen": overdose
When taking a large amount of medication, such side effects from the central nervous system as loss of consciousness, respiratory depression, drowsiness, and coma may appear. Other manifestations may also be noted. Among them: mental arousal, disturbance of accommodation, muscular hypotension. There is also a lack of a pupil reflex, convulsions, expansion of peripheral vessels, changes in EEG (three-phase waves and inhibition of outbreaks), arterial hypotension, tachyarrhythmia, tachycardia, bradycardia. The patient may experience vomiting or nausea, hypothermia, diarrhea, increased salivation. In patients with renal failure, signs of an overdose may appear when taking a small amount of the drug. The general condition may become worse during therapy with other agents. Such medicines include, for example, tricyclic antidepressants, Diazepam and other substances.
Elimination of complications
There is no specific antidote. In case of an overdose, symptomatic treatment is necessary. It is aimed at reducing the intensity of side effects associated with depression of the circulatory system or breathing, hypotension, convulsions. It is necessary to provoke vomiting as soon as possible or flush. Activated carbon recommended. If necessary, salt laxatives are prescribed. According to some data, in case of light poisoning, the injected Physiostigmine solution (1-2 mg in the first 5-10 minutes) is able to eliminate side effects from the central nervous system, in particular respiratory depression and drowsiness. If there is no effect, the next infusion Baclofen the solution is allowed after 30-60 minutes. The introduction of drugs at the same time as diuretics is recommended. This will enhance the excretion of Baclofen in the urine. In severe condition, hemodialysis is prescribed to patients with renal failure. If convulsions occur, the drug "Diazepam" is recommended. The medication is carefully injected into a vein. When breathing stops, artificial lung ventilation is performed and the cardiovascular system is maintained.
Additional Information
Keep the medication at a temperature below 25 degrees, in places inaccessible to children. Before using the product, you should carefully study the annotation. If side effects occur, including those not described above, you should immediately consult a doctor. During treatment, you should carefully follow the doctor’s recommendations and do not exceed the dosage.
