American scientists have found that the popular celecoxib arthritis medicine (Celebrex) helps with depression, enhancing the effect of antidepressants.
A report was published at the Fifth International Congress of Psychiatry and Neuroscience in Athens, according to which the combination of celecoxib with other drugs leads to a more pronounced and faster decrease in symptoms of depression in patients with bipolar disorder.
A recent study involved patients with bipolar disorder aged 18-65.
Both groups responded positively to treatment, but the first group showed better results: 73% of the participants achieved a reduction in symptoms of depression by at least 50%. In the control group, only 45% of participants achieved such results..
“Celecoxib prevents resistance to therapy and enhances the response to antidepressants in general. Such a combination, if used as early as possible, can significantly improve the neuroprogressive course of bipolar disorder, ”the authors said..
In addition to reducing the level of depression, scientists noted a quick recovery of patients. Usually, the stable effect of antidepressants develops within 4-6 weeks. During the study, depression began to recede in the first week of therapy, which is a kind of record.
Details of the work are published on the website of Loyola University in Chicago.